TB-Profiler result

Run: SRR18213841
Summary

Run ID: SRR18213841

Sample name:

Date: 03-04-2023 19:31:31

Number of reads: 5203742

Percentage reads mapped: 99.28

Strain: lineage4.8.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8.2 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7493 c.192C>T synonymous_variant 0.16
gyrA 8135 c.834C>T synonymous_variant 1.0
gyrA 8377 p.Asp359Gly missense_variant 0.16
fgd1 490696 c.-87T>G upstream_gene_variant 0.33
rpoC 764751 p.Val461Gly missense_variant 0.25
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776891 p.Gln530His missense_variant 1.0
mmpL5 777399 p.Thr361Arg missense_variant 0.46
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406898 p.Ala148Glu missense_variant 0.1
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
inhA 1674892 p.Asn231Asp missense_variant 0.21
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168149 p.Pro822Ser missense_variant 1.0
PPE35 2170156 p.Ala153Pro missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2290023 c.-782A>C upstream_gene_variant 0.22
eis 2714366 p.Val323Leu missense_variant 0.29
ahpC 2726756 c.564C>G synonymous_variant 0.23
Rv2752c 3064552 p.Arg547Pro missense_variant 0.2
Rv2752c 3064741 p.Gly484Ala missense_variant 0.52
thyX 3067995 c.-50A>C upstream_gene_variant 0.21
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
fprA 3474400 p.Tyr132Asp missense_variant 0.37
fprA 3475280 p.Val425Gly missense_variant 0.4
fprA 3475339 p.Ala445Pro missense_variant 0.15
fbiB 3642512 p.Leu326Phe missense_variant 0.16
fbiB 3642734 c.1200G>C synonymous_variant 0.16
alr 3841504 c.-84C>G upstream_gene_variant 0.17
rpoA 3878238 p.Asp90Glu missense_variant 0.15
clpC1 4039729 p.Asp326Asn missense_variant 1.0
clpC1 4039932 p.Gly258Val missense_variant 0.44
embC 4242369 p.Arg836Pro missense_variant 0.18
embC 4242476 p.Pro872Ala missense_variant 0.33
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242822 p.Val987Gly missense_variant 0.21
embB 4248725 p.Ser738Ala missense_variant 0.22
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0