TB-Profiler result

Run: SRR18213927
Summary

Run ID: SRR18213927

Sample name:

Date: 03-04-2023 19:35:07

Number of reads: 2950876

Percentage reads mapped: 99.53

Strain: lineage4.5

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.5 Euro-American H;T RD122 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7892 c.591G>A synonymous_variant 0.99
gyrA 9304 p.Gly668Asp missense_variant 0.97
fgd1 490751 c.-32T>G upstream_gene_variant 0.23
ccsA 620029 c.139C>T synonymous_variant 0.99
rpoB 759620 c.-187A>C upstream_gene_variant 0.12
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406101 p.Pro414Ser missense_variant 0.97
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170568 p.Ile15Met missense_variant 0.98
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2714529 c.804C>T synonymous_variant 1.0
ahpC 2726338 p.Val49Gly missense_variant 0.41
ahpC 2726341 p.Val50Gly missense_variant 0.33
thyA 3073806 c.666C>G synonymous_variant 0.27
Rv3083 3449746 p.Asp415Asn missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878575 c.-68C>T upstream_gene_variant 0.97
clpC1 4038318 p.Pro796Leu missense_variant 1.0
clpC1 4038857 c.1848C>A synonymous_variant 0.3
embA 4242643 c.-590C>T upstream_gene_variant 1.0
ethR 4327994 p.Thr149Met missense_variant 0.98
whiB6 4338595 c.-75delG upstream_gene_variant 1.0