TB-Profiler result

Run: SRR18337409
Summary

Run ID: SRR18337409

Sample name:

Date: 03-04-2023 19:38:05

Number of reads: 956575

Percentage reads mapped: 99.64

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 575891 p.Ala182Thr missense_variant 1.0
rpoB 761723 c.1917A>G synonymous_variant 0.11
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777346 p.Trp379Arg missense_variant 0.1
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
embR 1417481 c.-134G>C upstream_gene_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473783 n.126A>G non_coding_transcript_exon_variant 0.22
rrl 1473811 n.154C>A non_coding_transcript_exon_variant 0.18
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155812 c.300G>A synonymous_variant 0.14
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
fbiD 3339732 c.615C>A synonymous_variant 0.12
fprA 3474280 p.Glu92Lys missense_variant 0.1
whiB7 3568422 c.258G>A synonymous_variant 0.33
rpoA 3878630 c.-123G>C upstream_gene_variant 0.1
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4242928 c.-305A>G upstream_gene_variant 1.0
embB 4246584 p.Arg24Pro missense_variant 0.44
embB 4247595 p.Cys361Ser missense_variant 1.0
aftB 4267853 c.984G>A synonymous_variant 0.11
aftB 4268040 p.Leu266Pro missense_variant 1.0
ubiA 4269032 p.Gly268Cys missense_variant 0.13
ethR 4327924 p.Ala126Thr missense_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0