TB-Profiler result

Run: SRR19303810
Summary

Run ID: SRR19303810

Sample name:

Date: 03-04-2023 21:07:36

Number of reads: 8912517

Percentage reads mapped: 99.52

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 7158 p.Asp640Ala missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.23
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.33
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.33
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.33
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.4
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.25
rrl 1474798 n.1141C>G non_coding_transcript_exon_variant 0.25
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.25
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.25
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.29
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.29
rrl 1474825 n.1168G>A non_coding_transcript_exon_variant 0.29
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.29
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.29
rrl 1474837 n.1180A>G non_coding_transcript_exon_variant 0.25
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.29
rrl 1476193 n.2536A>G non_coding_transcript_exon_variant 0.29
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168149 p.Pro822Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
thyA 3074568 c.-97C>T upstream_gene_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.3
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
Rv3083 3448500 c.-4A>G upstream_gene_variant 1.0
Rv3083 3448501 c.-3G>T upstream_gene_variant 1.0
clpC1 4039729 p.Asp326Asn missense_variant 1.0
clpC1 4040093 c.612C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246481 c.-33C>A upstream_gene_variant 1.0
embB 4246584 p.Arg24Pro missense_variant 0.31
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0