TB-Profiler result

Run: SRR2100200
Summary

Run ID: SRR2100200

Sample name:

Date: 03-04-2023 22:50:49

Number of reads: 3837562

Percentage reads mapped: 99.69

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 0.93
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
rpoC 766085 p.Pro906Ala missense_variant 0.95
mmpL5 775639 p.Ile948Val missense_variant 0.99
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
atpE 1460992 c.-53A>C upstream_gene_variant 0.91
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.25
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474127 n.470G>A non_coding_transcript_exon_variant 0.4
rrl 1474300 n.643C>T non_coding_transcript_exon_variant 0.15
rpsA 1834028 p.Pro163Ser missense_variant 0.97
tlyA 1917972 c.33A>G synonymous_variant 0.98
PPE35 2168863 c.1750C>T synonymous_variant 0.47
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv3083 3448497 c.-7T>A upstream_gene_variant 0.25
Rv3083 3448835 p.Ser111Ile missense_variant 1.0
Rv3083 3449530 p.Val343Ile missense_variant 0.33
Rv3083 3449857 p.Pro452Ser missense_variant 0.22
fbiB 3641895 c.361C>T synonymous_variant 1.0
alr 3840764 c.657G>C synonymous_variant 0.91
rpoA 3878630 c.-124delC upstream_gene_variant 0.15
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338242 p.Gln94Glu missense_variant 0.38
whiB6 4338297 c.225G>A synonymous_variant 0.18
whiB6 4338361 p.Arg54Gln missense_variant 0.18
whiB6 4338432 c.90G>A synonymous_variant 0.67
whiB6 4338534 c.-13A>T upstream_gene_variant 0.5
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
whiB6 4336842 c.-14_*1328del transcript_ablation 1.0
whiB6 4336843 c.-13_*1327del transcript_ablation 1.0