TB-Profiler result

Run: SRR2101400
Summary

Run ID: SRR2101400

Sample name:

Date: 03-04-2023 23:41:39

Number of reads: 481845

Percentage reads mapped: 99.26

Strain: lineage4.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 7163 p.Ala642Pro missense_variant 0.14
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7704 p.Thr135Ala missense_variant 0.14
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 490594 c.-189C>A upstream_gene_variant 0.11
mshA 576250 c.903G>T synonymous_variant 0.1
ccsA 619787 c.-103delG upstream_gene_variant 0.15
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775690 p.Ala931Ser missense_variant 0.12
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303591 c.661C>A synonymous_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474920 n.1263G>T non_coding_transcript_exon_variant 0.11
rrl 1476563 n.2906G>T non_coding_transcript_exon_variant 0.12
fabG1 1674064 p.Lys209* stop_gained 0.18
inhA 1674440 p.Glu80Gly missense_variant 0.2
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154613 p.Gln500Arg missense_variant 0.14
katG 2154965 p.Ser383Thr missense_variant 0.12
PPE35 2167872 p.Ser914Leu missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv1979c 2223364 c.-200G>A upstream_gene_variant 0.14
eis 2714884 p.His150Arg missense_variant 0.12
ahpC 2726210 c.18T>C synonymous_variant 1.0
folC 2747576 p.Pro8Leu missense_variant 0.13
pepQ 2860230 c.188delA frameshift_variant 0.15
Rv2752c 3064568 p.Gly542Trp missense_variant 0.15
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3475267 p.Ala421Ser missense_variant 0.11
fbiA 3640425 c.-118T>C upstream_gene_variant 0.12
fbiA 3641447 p.Thr302Met missense_variant 1.0
fbiB 3642546 p.Gly338Ser missense_variant 0.15
rpoA 3877553 p.Glu319Lys missense_variant 1.0
rpoA 3877911 c.597G>A synonymous_variant 0.11
embC 4240266 p.Arg135Pro missense_variant 0.11
embC 4240685 p.Thr275Ala missense_variant 0.18
embC 4240897 c.1035C>G synonymous_variant 1.0
embC 4241704 c.1842C>T synonymous_variant 0.11
embC 4241939 p.Pro693Ser missense_variant 0.12
embC 4241965 c.2103C>T synonymous_variant 0.14
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4249408 c.2895G>A synonymous_variant 1.0
embB 4249473 p.Asp987Gly missense_variant 0.14
aftB 4266970 p.Pro623Thr missense_variant 0.18
aftB 4267334 c.1503T>C synonymous_variant 0.12
aftB 4267964 c.873T>A synonymous_variant 0.12
aftB 4268275 p.Glu188* stop_gained 0.11
ubiA 4269960 c.-127G>A upstream_gene_variant 0.11
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408022 p.Arg61Gly missense_variant 0.1