TB-Profiler result

Run: SRR2101618
Summary

Run ID: SRR2101618

Sample name:

Date: 03-04-2023 23:49:18

Number of reads: 624902

Percentage reads mapped: 99.85

Strain: lineage4.8.1

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
lineage4.8.1 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
ccsA 619831 c.-60T>C upstream_gene_variant 0.11
ccsA 620748 c.858T>G synonymous_variant 0.28
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471877 n.32A>T non_coding_transcript_exon_variant 0.11
rrl 1473979 n.322G>T non_coding_transcript_exon_variant 0.11
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1475944 n.2287G>A non_coding_transcript_exon_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168149 p.Pro822Ser missense_variant 1.0
PPE35 2169843 p.Ile257Thr missense_variant 0.29
PPE35 2170238 c.375T>C synonymous_variant 0.18
PPE35 2170394 c.219G>T synonymous_variant 0.13
PPE35 2170808 c.-196G>T upstream_gene_variant 0.13
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2715032 p.Cys101Gly missense_variant 0.11
ahpC 2726526 p.Ser112Pro missense_variant 0.15
fbiD 3339040 c.-78T>C upstream_gene_variant 1.0
fbiD 3339583 p.Thr156Ala missense_variant 0.18
fbiB 3642874 p.Leu447Arg missense_variant 1.0
alr 3840250 p.Val391Ile missense_variant 0.1
embC 4242248 p.Ala796Thr missense_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4245629 c.-885C>A upstream_gene_variant 0.11
embB 4246397 c.-117A>G upstream_gene_variant 0.1
ubiA 4269887 c.-55delC upstream_gene_variant 0.1
whiB6 4338250 p.Ala91Glu missense_variant 0.11
whiB6 4338318 c.204G>A synonymous_variant 0.14
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0