TB-Profiler result

Run: SRR21159786
Summary

Run ID: SRR21159786

Sample name:

Date: 21-05-2023 18:19:21

Number of reads: 8295698

Percentage reads mapped: 99.98

Strain: lineage4.9

Drug-resistance: Other

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Rifampicin
Isoniazid
Ethambutol
Pyrazinamide
Streptomycin
Fluoroquinolones
Moxifloxacin
Ofloxacin
Levofloxacin
Ciprofloxacin
Aminoglycosides R rrs n.1402C>T (1.00)
Amikacin R rrs n.1402C>T (1.00)
Capreomycin R rrs n.1402C>T (1.00)
Kanamycin R rrs n.1402C>T (1.00)
Cycloserine
Ethionamide
Clofazimine
Para-aminosalicylic_acid
Delamanid
Bedaquiline
Linezolid
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1473247 n.1402C>T non_coding_transcript_exon_variant 1.0 kanamycin, capreomycin, aminoglycosides, amikacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
mshA 576108 p.Ala254Gly missense_variant 0.29
Rv1258c 1406686 p.Val219Ile missense_variant 0.98
rrs 1471659 n.-187C>T upstream_gene_variant 1.0