TB-Profiler result

Run: SRR21674629

Summary

Run ID: SRR21674629

Sample name:

Date: 04-04-2023 02:33:55

Number of reads: 467170

Percentage reads mapped: 99.72

Strain: lineage4.8

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6247 p.Lys336Asn missense_variant 0.12
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 575255 c.-93G>A upstream_gene_variant 1.0
rpoC 764541 p.Val391Gly missense_variant 0.11
rpoC 764543 p.Thr392Ala missense_variant 0.11
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 778294 p.Ser63Ala missense_variant 0.22
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304222 p.Val431Glu missense_variant 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471856 n.11A>G non_coding_transcript_exon_variant 0.1
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474391 n.734G>T non_coding_transcript_exon_variant 0.2
rrl 1475392 n.1735C>A non_coding_transcript_exon_variant 0.14
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918130 p.Ser64* stop_gained 0.11
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 0.18
pepQ 2860043 p.Gly126* stop_gained 0.1
alr 3840764 c.657G>C synonymous_variant 1.0
panD 4044307 c.-26A>G upstream_gene_variant 0.12
embC 4240473 p.Leu204Arg missense_variant 0.18
embC 4240680 p.Leu273Pro missense_variant 0.17
embA 4242643 c.-590C>T upstream_gene_variant 1.0
ethR 4328102 p.Ala185Val missense_variant 0.14
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 0.1
gid 4408143 c.60G>A synonymous_variant 0.12
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0