TB-Profiler result

Run: SRR21708939
Summary

Run ID: SRR21708939

Sample name:

Date: 04-04-2023 02:58:25

Number of reads: 637333

Percentage reads mapped: 99.83

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304241 p.Glu437Asp missense_variant 0.1
Rv1258c 1406105 c.1236T>C synonymous_variant 1.0
Rv1258c 1406459 c.882G>T synonymous_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473460 n.-198G>A upstream_gene_variant 0.14
rrl 1475706 n.2050delT non_coding_transcript_exon_variant 0.11
inhA 1673658 c.-544G>A upstream_gene_variant 0.11
fabG1 1673683 p.Val82Phe missense_variant 0.12
rpsA 1834541 p.Pro334Ser missense_variant 0.1
rpsA 1834557 p.Ala339Asp missense_variant 0.11
rpsA 1834953 p.Ala471Glu missense_variant 0.13
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102792 p.Val84Ala missense_variant 0.12
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2290137 c.-897delT upstream_gene_variant 0.11
ahpC 2726341 p.Val50Gly missense_variant 0.25
rpoA 3877536 c.972C>T synonymous_variant 1.0
whiB6 4338472 p.Arg17Thr missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0