TB-Profiler result

Run: SRR21727728

Summary

Run ID: SRR21727728

Sample name:

Date: 04-04-2023 03:16:44

Number of reads: 2156791

Percentage reads mapped: 99.39

Strain: lineage4.4.1.1

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.4 Euro-American S;T None 1.0
lineage4.4.1 Euro-American (S-type) S;T None 1.0
lineage4.4.1.1 Euro-American S;Orphans None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304243 p.Pro438Leu missense_variant 1.0
Rv1258c 1406338 p.Val335Met missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474416 n.759C>T non_coding_transcript_exon_variant 0.12
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.1
rrl 1474628 n.971C>T non_coding_transcript_exon_variant 0.1
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.1
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.1
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.1
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.1
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.1
rrl 1474670 n.1013C>A non_coding_transcript_exon_variant 0.11
rrl 1474673 n.1016T>A non_coding_transcript_exon_variant 0.11
rrl 1474675 n.1019delT non_coding_transcript_exon_variant 0.11
rrl 1474678 n.1021G>T non_coding_transcript_exon_variant 0.11
rrl 1474679 n.1022G>C non_coding_transcript_exon_variant 0.11
rrl 1474683 n.1026C>G non_coding_transcript_exon_variant 0.11
rrl 1474684 n.1027T>C non_coding_transcript_exon_variant 0.11
rrl 1474688 n.1031G>A non_coding_transcript_exon_variant 0.11
rrl 1474709 n.1053_1056delTGGT non_coding_transcript_exon_variant 0.12
rrl 1474717 n.1060_1061insGTGAG non_coding_transcript_exon_variant 0.12
rrl 1474721 n.1064G>A non_coding_transcript_exon_variant 0.13
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.12
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.13
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.17
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.17
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.17
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.15
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.15
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.14
rrl 1476076 n.2419A>G non_coding_transcript_exon_variant 0.12
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.11
rrl 1476087 n.2430C>T non_coding_transcript_exon_variant 0.11
rrl 1476091 n.2434_2435insG non_coding_transcript_exon_variant 0.11
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.11
rrl 1476100 n.2443A>C non_coding_transcript_exon_variant 0.11
rrl 1476103 n.2446C>A non_coding_transcript_exon_variant 0.11
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.12
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 0.15
rrl 1476113 n.2456T>G non_coding_transcript_exon_variant 0.12
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.1
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102990 p.Val18Ala missense_variant 1.0
PPE35 2169840 p.Gly258Asp missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3448608 c.105G>A synonymous_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612665 p.Val151Ala missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4268614 p.Gly75Trp missense_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0