TB-Profiler result

Run: SRR22048352
Summary

Run ID: SRR22048352

Sample name:

Date: 04-04-2023 03:43:19

Number of reads: 4074869

Percentage reads mapped: 98.84

Strain: lineage4.2.2.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.2 Euro-American H;T;LAM None 1.0
lineage4.2.2 Euro-American (Ural) T;LAM7-TUR None 1.0
lineage4.2.2.2 Euro-American (Ural) T;LAM7-TUR None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8688 p.Ala463Ser missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576077 c.730C>T synonymous_variant 1.0
rpoB 761489 c.1683G>A synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.13
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.13
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.12
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.12
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.12
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.12
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.12
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.12
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.12
rrl 1474124 n.467G>C non_coding_transcript_exon_variant 0.11
rrl 1474125 n.468C>G non_coding_transcript_exon_variant 0.11
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 0.12
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.11
rrl 1474141 n.484G>C non_coding_transcript_exon_variant 0.11
rrl 1474142 n.485C>G non_coding_transcript_exon_variant 0.11
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.12
rrl 1474155 n.498G>A non_coding_transcript_exon_variant 0.12
rrl 1474171 n.514C>T non_coding_transcript_exon_variant 0.11
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.11
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.11
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.11
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.12
rrl 1474199 n.542G>A non_coding_transcript_exon_variant 0.11
rrl 1474202 n.545T>C non_coding_transcript_exon_variant 0.11
rrl 1475751 n.2094C>G non_coding_transcript_exon_variant 0.17
rrl 1475752 n.2095C>A non_coding_transcript_exon_variant 0.17
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.17
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.15
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.15
rrl 1475776 n.2119G>T non_coding_transcript_exon_variant 0.15
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.15
rrl 1475783 n.2126T>G non_coding_transcript_exon_variant 0.15
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.17
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 0.17
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.14
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.25
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.11
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.12
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.14
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.14
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.12
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.12
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.12
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.12
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.14
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2222681 p.Ala162Pro missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv2752c 3066280 c.-89C>T upstream_gene_variant 1.0
ald 3086742 c.-78A>C upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0