TB-Profiler result

Run: SRR22048377
Summary

Run ID: SRR22048377

Sample name:

Date: 04-04-2023 03:44:53

Number of reads: 1248253

Percentage reads mapped: 93.35

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.12
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.12
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.12
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.12
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.23
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.12
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.12
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.12
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.12
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.12
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.12
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.15
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.13
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.15
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.15
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 0.16
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.16
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.2
rrl 1474199 n.542G>C non_coding_transcript_exon_variant 0.17
rrl 1474200 n.545delT non_coding_transcript_exon_variant 0.17
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.24
rrl 1474271 n.614A>G non_coding_transcript_exon_variant 0.13
rrl 1474272 n.615C>T non_coding_transcript_exon_variant 0.14
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 0.15
rrl 1474443 n.786T>A non_coding_transcript_exon_variant 0.11
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.12
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.11
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.11
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.19
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.15
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.15
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.14
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.14
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.14
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.11
rrl 1474709 n.1052G>A non_coding_transcript_exon_variant 0.12
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.15
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.15
rrl 1475317 n.1660G>T non_coding_transcript_exon_variant 0.11
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.1
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.17
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.17
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.17
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.16
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.16
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.12
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.16
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.19
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.18
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.13
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.12
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.14
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.11
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.14
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.1
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.3
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.26
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.26
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.21
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168149 p.Pro822Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
fbiA 3640639 p.Ala33Thr missense_variant 0.1
rpoA 3878382 c.126G>A synonymous_variant 0.1
embC 4239930 p.Gly23Glu missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338380 p.Glu48* stop_gained 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407566 p.Arg213Gly missense_variant 1.0
Rv3083 3448497 c.-6_*1408del transcript_ablation 1.0