TB-Profiler result

Run: SRR23071987
Summary

Run ID: SRR23071987

Sample name:

Date: 13-03-2023 18:48:25

Number of reads: 5137062

Percentage reads mapped: 99.97

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472358 n.513C>T non_coding_transcript_exon_variant 0.99 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
mshA 576100 p.Asp251Glu missense_variant 0.23
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
pepQ 2860130 p.Phe97Val missense_variant 0.13
pepQ 2860153 p.Glu89Ala missense_variant 0.18
Rv2752c 3064846 p.Val449Gly missense_variant 0.13
rpoA 3878583 c.-76C>A upstream_gene_variant 0.14
rpoA 3878609 c.-102T>G upstream_gene_variant 0.16
embB 4248309 p.Phe599Cys missense_variant 0.13
panD 4043882 c.-896_399del start_lost&conservative_inframe_deletion 1.0