Run ID: SRR2667443
Sample name:
Date: 2024-04-14T19:56:04.268265
Number of reads: 153537
Percentage reads mapped: 1.03
Median coverage: 0.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: Sensitive
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage4 | Euro-American | None | 1.0 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 1.0 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | ||||
| pyrazinamide | ||||
| streptomycin | ||||
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | ||||
| para-aminosalicylic_acid | ||||
| delamanid | ||||
| bedaquiline | ||||
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| rrl | 1473571 | n.-87C>T | upstream_gene_variant | 0.98 | capreomycin | |
| linezolid | ||||||
| rrl | 1473585 | n.-73C>T | upstream_gene_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473589 | n.-69C>T | upstream_gene_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473592 | n.-66C>T | upstream_gene_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473601 | n.-57C>T | upstream_gene_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473603 | n.-55C>T | upstream_gene_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473606 | n.-52C>T | upstream_gene_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473607 | n.-51C>T | upstream_gene_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473610 | n.-48C>T | upstream_gene_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473614 | n.-44C>T | upstream_gene_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473620 | n.-38C>T | upstream_gene_variant | 0.98 | capreomycin | |
| linezolid | ||||||
| rrl | 1473626 | n.-32C>T | upstream_gene_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473633 | n.-25C>T | upstream_gene_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473640 | n.-18C>T | upstream_gene_variant | 0.98 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473668 | n.11C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473675 | n.18C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473677 | n.20C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| PPE35 | 2168663 | c.1950G>A | synonymous_variant | 1.0 | pyrazinamide | |
| PPE35 | 2168670 | p.Gly648Asn | missense_variant | 1.0 | pyrazinamide | |
| PPE35 | 2168679 | p.Ser645Asn | missense_variant | 1.0 | pyrazinamide | |
| PPE35 | 2168701 | p.Val638Ile | missense_variant | 1.0 | pyrazinamide | |
| PPE35 | 2168703 | p.Gly637Asn | missense_variant | 1.0 | pyrazinamide | |
| PPE35 | 2168713 | p.Ala634Thr | missense_variant | 0.98 | pyrazinamide | |
| PPE35 | 2168717 | c.1896G>A | synonymous_variant | 0.98 | pyrazinamide | |
| PPE35 | 2168722 | p.Ala631Thr | missense_variant | 1.0 | pyrazinamide | |
| PPE35 | 2168727 | p.Gly629Asn | missense_variant | 1.0 | pyrazinamide | |
| PPE35 | 2168736 | p.Ser626Asn | missense_variant | 1.0 | pyrazinamide | |
| PPE35 | 2168742 | p.Gly624Asn | missense_variant | 1.0 | pyrazinamide | |
| PPE35 | 2168745 | p.Gly623Asn | missense_variant | 1.0 | pyrazinamide | |
| PPE35 | 2168751 | p.Ser621Asn | missense_variant | 0.97 | pyrazinamide | |
| PPE35 | 2168766 | p.Ser616Asn | missense_variant | 1.0 | pyrazinamide | |
| PPE35 | 2168774 | c.1839G>A | synonymous_variant | 1.0 | pyrazinamide | |
| PPE35 | 2168786 | c.1827G>A | synonymous_variant | 1.0 | pyrazinamide | |
| PPE35 | 2168795 | c.1818G>A | synonymous_variant | 1.0 | pyrazinamide |
