TB-Profiler result

Run: SRR4034606
Summary

Run ID: SRR4034606

Sample name:

Date: 04-04-2023 06:55:04

Number of reads: 1052546

Percentage reads mapped: 99.79

Strain: lineage4.3.3

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.3 Euro-American (LAM) LAM;T RD115 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8040 p.Gly247Ser missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491014 c.234dupC frameshift_variant 0.18
mshA 576244 c.897C>A synonymous_variant 0.11
rpoB 760002 p.Glu66Lys missense_variant 0.12
rpoC 764995 c.1626C>G synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776690 c.1791C>T synonymous_variant 0.1
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
embR 1417038 p.Ser104Arg missense_variant 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1476056 n.2399G>A non_coding_transcript_exon_variant 0.97
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918590 p.Glu217Asp missense_variant 0.15
PPE35 2169368 c.1245A>G synonymous_variant 0.12
Rv1979c 2223051 p.Glu38Asp missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518919 p.Gly269Ser missense_variant 1.0
eis 2714299 p.Ala345Val missense_variant 0.14
eis 2715092 p.Gly81Cys missense_variant 0.12
Rv2752c 3065824 p.Pro123Leu missense_variant 1.0
Rv2752c 3067110 c.-919A>G upstream_gene_variant 0.17
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612177 c.940C>A synonymous_variant 0.14
clpC1 4038287 c.2418C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243738 p.Gln169Arg missense_variant 0.11
embA 4246392 c.3164delG frameshift_variant 0.13
embB 4247863 c.1350C>A synonymous_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0