TB-Profiler result

Run: SRR5485400
Summary

Run ID: SRR5485400

Sample name:

Date: 18-08-2022 08:28:44

Number of reads: 89216

Percentage reads mapped: 99.23

Strain:

Drug-resistance: MDR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761100 p.Gln432Glu missense_variant 1.0 rifampicin
rpsL 781822 p.Lys88Met missense_variant 1.0 streptomycin
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6633 p.Gly465Asp missense_variant 0.15
rrs 1472302 n.457G>C non_coding_transcript_exon_variant 0.2
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.38
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.14
pncA 2288909 p.Glu111Tyr missense_variant 0.2
pncA 2289237 p.Arg2Gln missense_variant 0.18
embB 4247527 c.1014G>A synonymous_variant 0.15
embB 4247596 p.Cys361* stop_gained 0.17