TB-Profiler result

Run: SRR5485403
Summary

Run ID: SRR5485403

Sample name:

Date: 18-08-2022 08:28:24

Number of reads: 128754

Percentage reads mapped: 98.93

Strain:

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761100 p.Gln432Glu missense_variant 1.0 rifampicin
rpsL 781822 p.Lys88Met missense_variant 1.0 streptomycin
embB 4247429 p.Met306Leu missense_variant 1.0 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.24
fabG1 1673285 c.-155A>C upstream_gene_variant 0.2
fabG1 1673298 c.-142A>C upstream_gene_variant 0.2
fabG1 1673398 c.-42A>C upstream_gene_variant 0.19
pncA 2289138 p.Leu35Arg missense_variant 0.18
pncA 2289229 p.Ile5Leu missense_variant 0.14