TB-Profiler result

Run: SRR5485544
Summary

Run ID: SRR5485544

Sample name:

Date: 18-08-2022 08:27:20

Number of reads: 97509

Percentage reads mapped: 99.02

Strain:

Drug-resistance: MDR-TB

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Trp missense_variant 0.93 rifampicin
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7634 c.333C>T synonymous_variant 0.18
rpoB 761228 p.Tyr474* stop_gained 0.18
rrs 1472302 n.457G>C non_coding_transcript_exon_variant 0.15
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.16
katG 2155091 p.Trp341Gly missense_variant 0.14
katG 2155098 c.1014C>A synonymous_variant 0.14
pncA 2289041 c.201G>A synonymous_variant 0.13
pncA 2289052 p.Tyr64His missense_variant 0.17
embB 4247348 p.Thr279Pro missense_variant 0.2