TB-Profiler result

Run: SRR5485559
Summary

Run ID: SRR5485559

Sample name:

Date: 18-08-2022 08:26:17

Number of reads: 135527

Percentage reads mapped: 99.14

Strain:

Drug-resistance: MDR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
rpsL 781687 p.Lys43Arg missense_variant 1.0 streptomycin
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
pncA 2289043 p.Ser67Pro missense_variant 1.0 pyrazinamide
embB 4247429 p.Met306Val missense_variant 0.95 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6503 p.Lys422Gln missense_variant 0.18
rpoB 761228 p.Tyr474* stop_gained 0.18
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.31