TB-Profiler result

Run: SRR5485571
Summary

Run ID: SRR5485571

Sample name:

Date: 18-08-2022 08:25:30

Number of reads: 107445

Percentage reads mapped: 99.36

Strain:

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
rpsL 781687 p.Lys43Arg missense_variant 1.0 streptomycin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 1.0 kanamycin, capreomycin, aminoglycosides, amikacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoB 761228 p.Tyr474* stop_gained 0.2
rpsL 781661 p.Cys34Trp missense_variant 0.14
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.21
pncA 2288924 p.Phe106Leu missense_variant 0.2
embB 4247348 p.Thr279Pro missense_variant 0.2
embB 4247352 p.Asp280Ala missense_variant 0.14