TB-Profiler result

Run: SRR5485582

Summary

Run ID: SRR5485582

Sample name:

Date: 18-08-2022 08:24:30

Number of reads: 113907

Percentage reads mapped: 99.02

Strain:

Drug-resistance: MDR-TB


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761128 p.Ser441Leu missense_variant 1.0 rifampicin
rpoB 761146 p.Arg447His missense_variant 0.17 rifampicin
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
embB 4247429 p.Met306Val missense_variant 1.0 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6746 p.Gln503Lys missense_variant 0.23
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.26
pncA 2289243 c.-3_-2insC upstream_gene_variant 1.0
eis 2715263 p.Phe24Leu missense_variant 0.17