TB-Profiler result

Run: SRR5485592
Summary

Run ID: SRR5485592

Sample name:

Date: 18-08-2022 08:23:38

Number of reads: 84148

Percentage reads mapped: 99.34

Strain:

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
rpsL 781822 p.Lys88Arg missense_variant 1.0 streptomycin
pncA 2288928 p.Gly105Asp missense_variant 1.0 pyrazinamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7585 p.Ser95Thr missense_variant 1.0
rpoB 761080 p.Phe425Ser missense_variant 0.14
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.32
rrs 1473229 n.1384T>C non_coding_transcript_exon_variant 0.18
pncA 2289013 p.Pro77Ser missense_variant 0.17
pncA 2289264 c.-23T>C upstream_gene_variant 0.17