TB-Profiler result

Run: SRR5485608
Summary

Run ID: SRR5485608

Sample name:

Date: 18-08-2022 08:22:30

Number of reads: 89196

Percentage reads mapped: 98.73

Strain:

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761140 p.His445Leu missense_variant 1.0 rifampicin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6625 c.-677G>A upstream_gene_variant 0.14
rpsL 781661 p.Cys34Trp missense_variant 0.17
rpsL 781679 c.120C>T synonymous_variant 1.0
rrs 1472302 n.457G>C non_coding_transcript_exon_variant 0.27
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.19
katG 2155241 p.Ala291Ser missense_variant 0.14
katG 2155267 p.Asp282Ala missense_variant 0.21
pncA 2288970 p.Glu91Gly missense_variant 0.14
eis 2715269 p.Ala22Thr missense_variant 0.18
embB 4247616 p.Glu368Gly missense_variant 0.17