TB-Profiler result

Run: SRR5818433
Summary

Run ID: SRR5818433

Sample name:

Date: 04-04-2023 11:29:10

Number of reads: 606454

Percentage reads mapped: 99.5

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7502 c.201C>T synonymous_variant 0.16
gyrA 7585 p.Ser95Thr missense_variant 1.0
mmpR5 779434 p.Val149Ile missense_variant 1.0
mmpL5 779478 c.-998C>T upstream_gene_variant 0.18
rrs 1472118 n.273A>G non_coding_transcript_exon_variant 0.22
rrs 1473047 n.1204delT non_coding_transcript_exon_variant 0.28
rrl 1476010 n.2353G>A non_coding_transcript_exon_variant 0.27
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.23
tlyA 1917972 c.33A>G synonymous_variant 1.0
ahpC 2726184 c.-9A>C upstream_gene_variant 0.4
ahpC 2726446 p.Val85Ala missense_variant 0.16
ahpC 2726471 c.279T>C synonymous_variant 0.17
embB 4247615 p.Glu368* stop_gained 0.15
embB 4247646 p.Glu378Ala missense_variant 1.0
ethA 4326764 p.Ala237Val missense_variant 0.29