TB-Profiler result

Run: SRR5818664
Summary

Run ID: SRR5818664

Sample name:

Date: 04-04-2023 11:41:34

Number of reads: 644911

Percentage reads mapped: 97.59

Strain: lineage4.7

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.7 Euro-American (mainly T) T1;T5 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6641 p.Lys468Glu missense_variant 0.12
gyrA 7362 p.Glu21Gln missense_variant 1.0
rpoB 759809 c.3G>T start_lost 0.11
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776018 c.2463G>C synonymous_variant 0.1
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473603 n.-55C>A upstream_gene_variant 0.18
rrl 1474294 n.637C>G non_coding_transcript_exon_variant 1.0
rrl 1476357 n.2700T>A non_coding_transcript_exon_variant 0.2
rrl 1476359 n.2702C>T non_coding_transcript_exon_variant 0.2
rrl 1476779 n.3122G>A non_coding_transcript_exon_variant 0.14
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2103173 c.-132delG upstream_gene_variant 0.11
katG 2154929 p.Arg395Cys missense_variant 0.11
PPE35 2170675 c.-63G>C upstream_gene_variant 1.0
Rv1979c 2222657 p.Lys170Glu missense_variant 0.12
Rv1979c 2222803 p.Ala121Val missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4245223 p.Tyr664Cys missense_variant 0.1
embB 4249732 c.3219C>G synonymous_variant 1.0
ethA 4327088 p.Leu129His missense_variant 0.13
whiB6 4338595 c.-75delG upstream_gene_variant 1.0