TB-Profiler result

Run: SRR6044896
Summary

Run ID: SRR6044896

Sample name:

Date: 04-04-2023 11:49:20

Number of reads: 2099651

Percentage reads mapped: 99.45

Strain: lineage4.8

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
embC 4240614 p.Leu251Arg missense_variant 1.0 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6815 p.Lys526Gln missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781676 c.117C>T synonymous_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472376 n.531G>T non_coding_transcript_exon_variant 0.17
rrs 1472379 n.534T>G non_coding_transcript_exon_variant 0.18
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.2
rrs 1472412 n.567A>G non_coding_transcript_exon_variant 0.18
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474383 n.726G>T non_coding_transcript_exon_variant 0.2
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 0.22
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.33
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.25
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.25
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.25
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.25
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.25
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.2
rrl 1474674 n.1017A>C non_coding_transcript_exon_variant 0.18
rrl 1474675 n.1018C>A non_coding_transcript_exon_variant 0.18
rrl 1474676 n.1019T>C non_coding_transcript_exon_variant 0.18
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.18
rrl 1474694 n.1037C>T non_coding_transcript_exon_variant 0.2
rrl 1475449 n.1792C>A non_coding_transcript_exon_variant 0.18
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.12
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.13
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.12
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.1
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.1
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.1
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.1
rrl 1475995 n.2338G>C non_coding_transcript_exon_variant 0.11
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.11
rrl 1475998 n.2341C>G non_coding_transcript_exon_variant 0.11
rrl 1475999 n.2342G>T non_coding_transcript_exon_variant 0.11
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.13
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
alr 3840764 c.657G>C synonymous_variant 1.0
rpoA 3878639 c.-132C>G upstream_gene_variant 0.18
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0