TB-Profiler result

Run: SRR6045264
Summary

Run ID: SRR6045264

Sample name:

Date: 04-04-2023 11:55:54

Number of reads: 496523

Percentage reads mapped: 13.1

Strain: lineage2.2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 0.99
lineage2.2 East-Asian (Beijing) Beijing-RD207 RD105;RD207 0.99
lineage2.2.1 East-Asian (Beijing) Beijing-RD181 RD105;RD207;RD181 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5661 p.Arg141Leu missense_variant 0.18
gyrB 6061 c.822C>T synonymous_variant 0.18
gyrA 6673 c.-629A>C upstream_gene_variant 0.17
gyrA 6676 c.-626T>C upstream_gene_variant 0.17
gyrA 6685 c.-617C>T upstream_gene_variant 0.15
gyrA 6700 c.-602T>C upstream_gene_variant 0.15
gyrA 6703 c.-599G>C upstream_gene_variant 0.15
gyrA 6709 c.-593A>G upstream_gene_variant 0.18
gyrA 6730 c.-572A>G upstream_gene_variant 0.18
gyrA 7033 c.-269G>T upstream_gene_variant 0.18
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491466 p.Met228Ile missense_variant 0.2
fgd1 491610 c.828A>G synonymous_variant 0.16
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575649 p.Val101Glu missense_variant 0.17
mshA 575907 p.Ala187Val missense_variant 0.92
mshA 576645 p.Thr433Asn missense_variant 0.14
ccsA 620020 p.Leu44Phe missense_variant 0.14
ccsA 620583 c.693G>C synonymous_variant 0.15
ccsA 620589 c.699G>C synonymous_variant 0.15
ccsA 620598 c.708C>G synonymous_variant 0.15
ccsA 620604 c.714C>G synonymous_variant 0.15
ccsA 620607 c.717T>A synonymous_variant 0.15
ccsA 620625 p.Ile245Met missense_variant 1.0
rpoB 760430 c.624T>C synonymous_variant 0.14
rpoB 761253 p.Pro483Ser missense_variant 0.14
rpoB 761276 c.1470G>A synonymous_variant 0.14
rpoB 762834 p.Gly1010Ser missense_variant 0.22
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763052 c.-318G>C upstream_gene_variant 0.21
rpoC 763070 c.-300T>C upstream_gene_variant 0.3
rpoC 763076 c.-294C>G upstream_gene_variant 0.3
rpoC 763082 c.-288C>G upstream_gene_variant 0.3
rpoC 763085 c.-285C>G upstream_gene_variant 0.3
rpoC 763094 c.-276G>C upstream_gene_variant 0.36
rpoC 763115 c.-255T>C upstream_gene_variant 0.42
rpoC 763166 c.-204A>G upstream_gene_variant 0.4
rpoC 763169 c.-201A>G upstream_gene_variant 0.33
rpoC 763184 c.-186C>T upstream_gene_variant 0.31
rpoC 763202 c.-168A>G upstream_gene_variant 0.29
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 0.27
rpoC 763226 c.-144A>G upstream_gene_variant 0.31
rpoC 763238 c.-132T>C upstream_gene_variant 0.36
rpoC 763268 c.-102C>A upstream_gene_variant 0.22
rpoC 763441 c.72C>T synonymous_variant 0.19
rpoC 763444 c.75T>C synonymous_variant 0.19
rpoC 763456 c.87A>G synonymous_variant 0.22
rpoC 763486 c.117T>G synonymous_variant 0.29
rpoC 763528 c.159G>A synonymous_variant 0.33
rpoC 763537 c.168C>G synonymous_variant 0.29
rpoC 763546 c.177A>G synonymous_variant 0.28
rpoC 763570 c.201G>C synonymous_variant 0.19
rpoC 763573 c.204G>C synonymous_variant 0.13
rpoC 763822 c.453C>A synonymous_variant 0.15
rpoC 763836 p.Ala156Val missense_variant 0.15
rpoC 763851 p.Ala161Gly missense_variant 0.2
rpoC 763855 c.486C>T synonymous_variant 0.2
rpoC 763858 c.489A>G synonymous_variant 0.2
rpoC 763871 p.Gly168Thr missense_variant 0.25
rpoC 763879 c.510A>G synonymous_variant 0.22
rpoC 763888 c.519G>T synonymous_variant 0.2
rpoC 763894 c.525A>G synonymous_variant 0.18
rpoC 764044 c.675T>C synonymous_variant 0.15
rpoC 764059 c.690G>C synonymous_variant 0.31
rpoC 764071 c.702G>C synonymous_variant 0.33
rpoC 764083 c.714A>G synonymous_variant 0.4
rpoC 764098 c.729A>G synonymous_variant 0.33
rpoC 764101 c.732C>G synonymous_variant 0.36
rpoC 764110 c.741C>T synonymous_variant 0.46
rpoC 764320 c.951C>G synonymous_variant 0.22
rpoC 764338 c.969G>A synonymous_variant 0.25
rpoC 764339 c.970C>T synonymous_variant 0.25
rpoC 764380 c.1011G>C synonymous_variant 0.22
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.22
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.29
rpoC 764809 c.1440C>T synonymous_variant 0.15
rpoC 764815 c.1446A>G synonymous_variant 0.17
rpoC 764824 c.1455T>C synonymous_variant 0.17
rpoC 764830 c.1461C>G synonymous_variant 0.16
rpoC 764858 c.1489_1491delTTGinsCTA synonymous_variant 0.14
rpoC 764861 c.1492C>T synonymous_variant 0.14
rpoC 764867 c.1498_1500delCGCinsAGG synonymous_variant 0.14
rpoC 764878 c.1509C>G synonymous_variant 0.12
rpoC 764881 c.1512G>C synonymous_variant 0.12
rpoC 765029 p.Glu554* stop_gained 0.15
rpoC 766345 c.2976T>C synonymous_variant 0.19
rpoC 766348 c.2979A>G synonymous_variant 0.15
rpoC 766381 c.3012C>T synonymous_variant 0.17
rpoC 766384 c.3015A>G synonymous_variant 0.15
rpoC 766393 c.3024C>G synonymous_variant 0.14
rpoC 766408 c.3039C>G synonymous_variant 0.18
rpoC 766426 c.3057C>T synonymous_variant 0.25
rpoC 766447 c.3078T>C synonymous_variant 0.13
rpoC 766456 c.3087C>G synonymous_variant 0.18
rpoC 766522 c.3153C>G synonymous_variant 0.15
rpoC 766528 c.3159T>C synonymous_variant 0.15
rpoC 766540 p.Asp1057Glu missense_variant 0.12
rpoC 766645 p.Glu1092Asp missense_variant 0.93
rpoC 766804 c.3435A>G synonymous_variant 0.27
rpoC 766861 c.3492G>A synonymous_variant 0.43
rpoC 766864 c.3495G>C synonymous_variant 0.43
rpoC 766883 p.Ser1172Ala missense_variant 0.4
rpoC 766894 c.3525T>C synonymous_variant 0.4
rpoC 766895 c.3526T>C synonymous_variant 0.4
rpoC 766900 c.3531T>C synonymous_variant 0.4
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775883 p.Ile866Leu missense_variant 0.16
mmpL5 775909 p.Leu858Phe missense_variant 0.21
mmpL5 775913 p.Ala856Ser missense_variant 0.21
mmpL5 775916 c.2565T>G synonymous_variant 0.21
mmpL5 775937 c.2544G>C synonymous_variant 0.2
mmpL5 775961 c.2520C>G synonymous_variant 0.17
mmpL5 775966 p.Ala839Ser missense_variant 0.18
mmpL5 775991 c.2490G>A synonymous_variant 0.12
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776182 p.Asp767Asn missense_variant 1.0
mmpL5 777775 p.Val236Leu missense_variant 0.14
mmpL5 778209 p.Ala91Val missense_variant 0.33
mmpL5 778287 p.Ser65Asn missense_variant 0.2
mmpS5 778588 p.Gln106His missense_variant 0.56
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 801222 c.414T>C synonymous_variant 0.14
rplC 801270 c.462T>C synonymous_variant 0.14
rplC 801276 c.468G>T synonymous_variant 0.13
rplC 801288 c.480G>C synonymous_variant 0.14
fbiC 1303575 c.645G>C synonymous_variant 0.14
fbiC 1303584 c.654C>G synonymous_variant 0.14
fbiC 1303990 c.1064delG frameshift_variant 0.2
fbiC 1304580 c.1650T>C synonymous_variant 0.17
fbiC 1304613 c.1683T>C synonymous_variant 0.19
fbiC 1304640 c.1710A>C synonymous_variant 0.12
fbiC 1304646 c.1716T>C synonymous_variant 0.2
fbiC 1304670 c.1740G>C synonymous_variant 0.23
fbiC 1304671 p.Val581Thr missense_variant 0.23
fbiC 1304675 p.Gly582Glu missense_variant 0.23
fbiC 1304691 c.1761G>C synonymous_variant 0.23
fbiC 1304694 c.1764A>C synonymous_variant 0.23
fbiC 1304703 c.1773C>G synonymous_variant 0.27
fbiC 1304715 c.1785G>C synonymous_variant 0.29
fbiC 1304724 c.1794A>G synonymous_variant 0.24
fbiC 1304727 c.1797A>G synonymous_variant 0.17
fbiC 1304757 c.1827A>G synonymous_variant 0.17
fbiC 1304778 c.1848T>C synonymous_variant 0.17
fbiC 1304784 c.1854T>G synonymous_variant 0.13
fbiC 1304787 c.1857T>C synonymous_variant 0.15
fbiC 1304799 c.1869G>C synonymous_variant 0.15
fbiC 1304808 c.1878C>G synonymous_variant 0.18
fbiC 1304811 c.1881C>G synonymous_variant 0.17
fbiC 1304817 c.1887T>C synonymous_variant 0.23
fbiC 1304823 c.1893C>T synonymous_variant 0.21
fbiC 1304829 c.1899T>C synonymous_variant 0.2
fbiC 1304853 c.1923C>T synonymous_variant 0.19
fbiC 1304856 c.1926C>G synonymous_variant 0.18
fbiC 1304869 c.1939C>T synonymous_variant 0.17
Rv1258c 1406760 c.580_581insC frameshift_variant 1.0
Rv1258c 1406978 p.Met121Ile missense_variant 0.18
embR 1417062 c.285delC frameshift_variant 0.17
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.16
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.17
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.19
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.18
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 0.19
rrs 1472574 n.729T>A non_coding_transcript_exon_variant 0.19
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.2
rrs 1472591 n.746G>A non_coding_transcript_exon_variant 0.15
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.23
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.2
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.2
rrs 1472970 n.1125C>T non_coding_transcript_exon_variant 0.18
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.24
rrs 1473234 n.1389A>T non_coding_transcript_exon_variant 0.2
rrl 1473389 n.-269C>A upstream_gene_variant 0.17
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.2
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.18
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.16
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.15
rrl 1473899 n.242A>T non_coding_transcript_exon_variant 0.15
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.14
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.15
rrl 1474040 n.383G>A non_coding_transcript_exon_variant 0.15
rrl 1474089 n.432C>T non_coding_transcript_exon_variant 0.23
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 0.2
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.18
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.3
rrl 1474249 n.592G>A non_coding_transcript_exon_variant 0.22
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.2
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.19
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.19
rrl 1474837 n.1180A>G non_coding_transcript_exon_variant 0.15
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.18
rrl 1474950 n.1293G>A non_coding_transcript_exon_variant 0.21
rrl 1474952 n.1296_1300delCATCC non_coding_transcript_exon_variant 0.21
rrl 1474961 n.1304T>G non_coding_transcript_exon_variant 0.21
rrl 1474962 n.1305T>C non_coding_transcript_exon_variant 0.21
rrl 1474963 n.1306G>A non_coding_transcript_exon_variant 0.21
rrl 1474964 n.1307T>A non_coding_transcript_exon_variant 0.21
rrl 1474967 n.1311_1315delGGGTG non_coding_transcript_exon_variant 0.19
rrl 1474997 n.1340A>T non_coding_transcript_exon_variant 0.19
rrl 1475006 n.1349A>G non_coding_transcript_exon_variant 0.2
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.17
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.25
rrl 1475253 n.1596T>G non_coding_transcript_exon_variant 0.25
rrl 1475606 n.1949T>C non_coding_transcript_exon_variant 0.18
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.2
rrl 1475616 n.1959A>G non_coding_transcript_exon_variant 0.2
rrl 1475617 n.1960C>G non_coding_transcript_exon_variant 0.2
rrl 1475625 n.1968G>C non_coding_transcript_exon_variant 0.2
rrl 1475626 n.1969T>C non_coding_transcript_exon_variant 0.2
rrl 1475639 n.1982C>T non_coding_transcript_exon_variant 0.17
rrl 1475883 n.2226A>G non_coding_transcript_exon_variant 0.22
rrl 1476226 n.2569G>T non_coding_transcript_exon_variant 0.29
inhA 1674333 c.132G>A synonymous_variant 0.18
inhA 1674792 c.591G>C synonymous_variant 0.14
inhA 1674801 c.600T>C synonymous_variant 0.15
inhA 1674816 c.615T>A synonymous_variant 0.14
inhA 1674822 c.621C>G synonymous_variant 0.15
inhA 1674825 c.624C>T synonymous_variant 0.19
inhA 1674846 c.645C>A synonymous_variant 0.29
inhA 1674849 p.Gln216His missense_variant 0.29
inhA 1674870 c.669T>C synonymous_variant 0.31
inhA 1674876 c.675C>G synonymous_variant 0.31
inhA 1674879 c.678T>G synonymous_variant 0.27
inhA 1674883 p.Ile228Leu missense_variant 0.25
inhA 1674903 c.702T>C synonymous_variant 0.24
inhA 1674904 p.Ala235Pro missense_variant 0.24
inhA 1674933 c.732G>C synonymous_variant 0.27
inhA 1674939 c.738G>C synonymous_variant 0.15
inhA 1674942 c.741T>G synonymous_variant 0.14
inhA 1674945 p.Asp248Glu missense_variant 0.2
inhA 1674957 c.756G>A synonymous_variant 0.14
rpsA 1833517 c.-24delC upstream_gene_variant 0.18
rpsA 1833541 c.-1T>C upstream_gene_variant 0.21
rpsA 1833554 p.Thr5Ala missense_variant 0.25
rpsA 1833578 p.Val13Ile missense_variant 0.17
rpsA 1834177 c.636A>C synonymous_variant 1.0
rpsA 1834411 c.870T>C synonymous_variant 0.14
rpsA 1834417 c.876G>C synonymous_variant 0.18
rpsA 1834423 c.882G>C synonymous_variant 0.18
rpsA 1834451 c.910T>C synonymous_variant 0.2
rpsA 1834456 c.915T>G synonymous_variant 0.19
rpsA 1834465 c.924T>C synonymous_variant 0.15
rpsA 1834468 c.927A>G synonymous_variant 0.2
rpsA 1834489 c.948T>C synonymous_variant 0.17
tlyA 1917798 c.-142C>A upstream_gene_variant 0.22
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2156354 c.-243G>T upstream_gene_variant 0.25
katG 2156545 c.-434G>T upstream_gene_variant 0.12
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2169484 p.Ala377Ser missense_variant 0.25
PPE35 2170031 c.582C>A synonymous_variant 0.25
Rv1979c 2222385 c.780C>A synonymous_variant 0.18
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2290104 c.-863G>T upstream_gene_variant 0.2
kasA 2518567 c.453G>C synonymous_variant 0.14
kasA 2518571 p.Val153Thr missense_variant 0.14
kasA 2518574 p.Ile154Val missense_variant 0.15
kasA 2518579 c.465T>G synonymous_variant 0.17
kasA 2518588 c.474T>G synonymous_variant 0.18
kasA 2518594 c.480C>G synonymous_variant 0.23
kasA 2518603 c.489G>A synonymous_variant 0.25
kasA 2518627 c.513T>C synonymous_variant 0.23
kasA 2518642 c.528A>G synonymous_variant 0.17
kasA 2518645 c.531G>C synonymous_variant 0.17
kasA 2519239 c.1125A>C synonymous_variant 0.2
kasA 2519272 c.1158C>G synonymous_variant 0.14
eis 2715427 c.-95T>C upstream_gene_variant 0.15
ahpC 2726265 p.Lys25Gln missense_variant 0.33
ahpC 2726338 p.Val49Gly missense_variant 0.29
ahpC 2726450 c.258G>T synonymous_variant 0.17
folC 2746527 p.Gly358Trp missense_variant 0.2
folC 2746816 c.783C>A synonymous_variant 0.14
folC 2747302 c.297A>G synonymous_variant 0.16
folC 2747335 c.264G>A synonymous_variant 0.13
folC 2747338 c.261C>G synonymous_variant 0.13
folC 2747341 p.Val86Leu missense_variant 0.2
folC 2747344 c.255G>C synonymous_variant 0.14
folC 2747355 p.Val82Ile missense_variant 0.13
folC 2747359 c.238_240delCGCinsAGG synonymous_variant 0.2
folC 2747362 p.Ala79Thr missense_variant 0.13
pepQ 2859825 p.Ala198Pro missense_variant 0.17
pepQ 2859834 c.585T>C synonymous_variant 0.15
ribD 2986995 p.Ala53Ser missense_variant 0.14
thyX 3067883 c.63C>G synonymous_variant 0.13
thyX 3067886 c.60A>G synonymous_variant 0.13
thyX 3067894 c.52T>C synonymous_variant 0.14
thyX 3067898 p.Asp16Glu missense_variant 0.14
thyA 3074367 c.105C>A synonymous_variant 0.14
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087578 c.759A>G synonymous_variant 0.14
ald 3087587 c.768G>A synonymous_variant 0.14
ald 3087641 c.822T>C synonymous_variant 0.13
ald 3087647 c.828A>G synonymous_variant 0.13
ald 3087649 p.Gly277Asp missense_variant 0.13
ald 3087653 c.834A>C synonymous_variant 0.13
ald 3087656 c.837A>G synonymous_variant 0.14
ald 3087659 c.840G>C synonymous_variant 0.15
ald 3087666 p.Tyr283His missense_variant 0.15
ald 3087671 c.852C>T synonymous_variant 0.21
ald 3087698 c.879G>C synonymous_variant 0.15
ald 3087704 c.885T>C synonymous_variant 0.14
fbiD 3339744 c.627A>T synonymous_variant 0.18
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474237 c.231C>A synonymous_variant 0.12
fprA 3475032 c.1026C>T synonymous_variant 0.15
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0
fbiB 3641073 c.-462T>G upstream_gene_variant 0.13
fbiB 3641097 c.-438T>C upstream_gene_variant 0.13
fbiB 3641100 c.-435T>A upstream_gene_variant 0.13
fbiB 3641112 c.-423T>C upstream_gene_variant 0.13
fbiA 3641118 p.Lys192Asn missense_variant 0.13
fbiA 3641119 p.Ser193Ala missense_variant 0.13
alr 3840864 p.Asp186Val missense_variant 0.14
rpoA 3877494 p.Glu338Asp missense_variant 0.14
rpoA 3877503 c.1005G>C synonymous_variant 0.15
rpoA 3877515 c.993G>C synonymous_variant 0.15
rpoA 3877557 c.951C>G synonymous_variant 0.14
rpoA 3877587 c.921A>G synonymous_variant 0.19
rpoA 3877613 p.Ile299Val missense_variant 0.25
rpoA 3877638 c.870T>C synonymous_variant 0.2
rpoA 3877743 c.765T>C synonymous_variant 0.19
rpoA 3877764 c.744C>G synonymous_variant 0.14
rpoA 3877782 c.726T>C synonymous_variant 0.12
rpoA 3877818 c.690A>G synonymous_variant 0.15
rpoA 3877839 c.669G>C synonymous_variant 0.14
rpoA 3878046 c.462T>C synonymous_variant 0.17
rpoA 3878055 c.453A>G synonymous_variant 0.16
rpoA 3878067 c.441C>G synonymous_variant 0.22
rpoA 3878094 c.414C>G synonymous_variant 0.15
rpoA 3878103 c.405A>G synonymous_variant 0.15
rpoA 3878106 c.402G>C synonymous_variant 0.16
rpoA 3878118 c.390T>C synonymous_variant 0.22
rpoA 3878130 c.378C>G synonymous_variant 0.22
rpoA 3878160 c.348C>G synonymous_variant 0.27
rpoA 3878163 c.345C>T synonymous_variant 0.38
rpoA 3878169 c.339G>C synonymous_variant 0.19
rpoA 3878313 c.195G>C synonymous_variant 0.18
rpoA 3878322 c.186A>G synonymous_variant 0.18
rpoA 3878331 c.177A>G synonymous_variant 0.14
rpoA 3878361 c.147G>C synonymous_variant 0.15
rpoA 3878364 c.144A>C synonymous_variant 0.15
rpoA 3878385 c.123C>G synonymous_variant 0.18
rpoA 3878409 c.99C>G synonymous_variant 0.18
rpoA 3878488 p.Pro7His missense_variant 0.29
clpC1 4038368 c.2337T>C synonymous_variant 0.14
clpC1 4038395 c.2310C>T synonymous_variant 0.13
clpC1 4038398 c.2307G>C synonymous_variant 0.13
clpC1 4038403 c.2302T>C synonymous_variant 0.13
clpC1 4038433 c.2272C>T synonymous_variant 0.18
clpC1 4038444 p.Ala754Lys missense_variant 0.15
clpC1 4038446 c.2259T>C synonymous_variant 0.15
clpC1 4038456 p.Val750Glu missense_variant 0.16
clpC1 4038494 c.2211G>C synonymous_variant 0.23
clpC1 4038499 p.Ser736Gly missense_variant 0.21
clpC1 4038530 p.Glu725Asp missense_variant 0.17
clpC1 4038559 p.Ile716Val missense_variant 0.15
clpC1 4038560 p.Asp715Glu missense_variant 0.15
clpC1 4038755 c.1950G>C synonymous_variant 0.18
clpC1 4038773 c.1932T>C synonymous_variant 0.29
clpC1 4038812 c.1893T>C synonymous_variant 0.31
clpC1 4038815 c.1890G>A synonymous_variant 0.25
clpC1 4039345 p.Glu454* stop_gained 0.13
clpC1 4039346 c.1359G>C synonymous_variant 0.13
clpC1 4039463 c.1242C>G synonymous_variant 0.18
clpC1 4039466 c.1239T>C synonymous_variant 0.18
clpC1 4039469 c.1236T>C synonymous_variant 0.18
clpC1 4039481 c.1224T>C synonymous_variant 0.2
clpC1 4039484 c.1221T>C synonymous_variant 0.16
clpC1 4039574 p.Ala377Ser missense_variant 0.16
clpC1 4039610 c.1095G>C synonymous_variant 0.18
clpC1 4039616 c.1089G>C synonymous_variant 0.18
clpC1 4039661 c.1044T>C synonymous_variant 0.24
clpC1 4039664 c.1041G>C synonymous_variant 0.22
clpC1 4039679 c.1026C>T synonymous_variant 0.22
clpC1 4039682 c.1023C>G synonymous_variant 0.33
clpC1 4039694 c.1011G>C synonymous_variant 0.25
clpC1 4039757 c.948A>G synonymous_variant 0.14
clpC1 4039760 c.945T>C synonymous_variant 0.15
clpC1 4039766 c.939T>C synonymous_variant 0.15
clpC1 4039769 c.936C>G synonymous_variant 0.15
clpC1 4039775 c.930G>C synonymous_variant 0.15
clpC1 4039778 c.927A>G synonymous_variant 0.13
clpC1 4039790 c.915C>G synonymous_variant 0.14
clpC1 4039898 c.807C>G synonymous_variant 0.18
clpC1 4039904 c.801A>G synonymous_variant 0.17
clpC1 4039913 c.792C>T synonymous_variant 0.15
clpC1 4039916 c.789T>C synonymous_variant 0.15
clpC1 4039925 c.780C>T synonymous_variant 0.14
clpC1 4039931 c.774T>C synonymous_variant 0.15
clpC1 4039934 c.771G>C synonymous_variant 0.15
clpC1 4039937 c.768G>C synonymous_variant 0.13
clpC1 4040354 c.351A>G synonymous_variant 0.13
clpC1 4040363 c.342A>T synonymous_variant 0.14
clpC1 4040381 c.324T>C synonymous_variant 0.14
clpC1 4040387 c.318A>G synonymous_variant 0.2
clpC1 4040393 c.312G>C synonymous_variant 0.18
clpC1 4040411 c.294T>C synonymous_variant 0.15
clpC1 4040423 c.282A>G synonymous_variant 0.16
clpC1 4040426 c.279T>C synonymous_variant 0.16
clpC1 4040431 c.274T>C synonymous_variant 0.16
clpC1 4040872 c.-168C>G upstream_gene_variant 0.18
embC 4240111 c.249C>T synonymous_variant 0.19
embC 4240120 c.258C>G synonymous_variant 0.19
embC 4240141 c.279A>G synonymous_variant 0.16
embC 4240154 c.293_301delAGAACACCG disruptive_inframe_deletion 0.17
embC 4240165 c.305_307delAGA disruptive_inframe_deletion 0.16
embC 4240178 c.316T>C synonymous_variant 0.21
embC 4240183 c.321A>G synonymous_variant 0.22
embC 4240201 c.339G>C synonymous_variant 0.24
embC 4240204 c.342T>G synonymous_variant 0.24
embC 4240211 p.Val117Ile missense_variant 0.13
embC 4240216 c.354T>C synonymous_variant 0.13
embC 4240228 c.366G>C synonymous_variant 0.13
embC 4240229 p.Leu123Ile missense_variant 0.14
embC 4240234 c.372A>G synonymous_variant 0.17
embC 4240237 c.375G>C synonymous_variant 0.15
embC 4240258 c.396T>G synonymous_variant 0.12
embC 4240828 c.966G>C synonymous_variant 0.13
embC 4240831 c.969T>G synonymous_variant 0.13
embC 4240879 c.1017G>C synonymous_variant 0.2
embC 4240885 c.1023T>C synonymous_variant 0.2
embC 4240897 c.1035C>G synonymous_variant 0.31
embC 4240898 c.1036C>T synonymous_variant 0.31
embC 4240911 p.Ala350Val missense_variant 0.27
embC 4240921 c.1059C>G synonymous_variant 0.29
embC 4240936 c.1074A>G synonymous_variant 0.21
embC 4240957 c.1095C>G synonymous_variant 0.2
embC 4240960 c.1098G>C synonymous_variant 0.2
embC 4240966 c.1104G>T synonymous_variant 0.2
embC 4240969 c.1107C>T synonymous_variant 0.2
embC 4240979 p.Thr373Gln missense_variant 0.18
embC 4240990 c.1128A>C synonymous_variant 0.18
embC 4241002 c.1140G>C synonymous_variant 0.18
embC 4241715 p.Asn618Ile missense_variant 0.15
embC 4241717 p.Arg619Trp missense_variant 0.15
embC 4242059 p.Ala733Ser missense_variant 0.14
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243024 c.-209T>C upstream_gene_variant 0.13
embA 4243460 c.228C>T synonymous_variant 1.0
embA 4244708 c.1476C>G synonymous_variant 0.3
embA 4244726 p.Asp498Glu missense_variant 0.3
embA 4244728 p.Phe499Trp missense_variant 0.33
embA 4244747 c.1515T>C synonymous_variant 0.43
embA 4244756 c.1524G>A synonymous_variant 0.5
embA 4244764 p.Val511Ala missense_variant 0.43
embA 4244771 c.1539G>T synonymous_variant 0.43
embA 4244780 c.1548C>G synonymous_variant 0.38
embA 4244783 c.1551C>G synonymous_variant 0.38
embA 4244792 c.1560G>C synonymous_variant 0.38
embA 4244802 p.Leu524Met missense_variant 0.33
embA 4244808 p.Phe526Leu missense_variant 0.33
embA 4244823 p.Val531Met missense_variant 0.33
embA 4244829 p.Phe533Val missense_variant 0.33
embA 4244843 c.1611G>C synonymous_variant 0.25
embA 4244996 c.1764C>A synonymous_variant 0.18
embB 4246268 c.-246G>A upstream_gene_variant 0.13
embB 4246277 c.-237G>C upstream_gene_variant 0.14
embB 4246280 c.-234G>C upstream_gene_variant 0.14
embB 4246292 c.-222A>G upstream_gene_variant 0.12
embA 4246305 p.Ser1025Ala missense_variant 0.12
embB 4246316 c.-198T>C upstream_gene_variant 0.13
embB 4246922 p.Arg137Ser missense_variant 0.15
embB 4247269 c.756C>A synonymous_variant 0.13
embB 4248867 p.Pro785Gln missense_variant 0.13
embB 4249757 p.Thr1082Ala missense_variant 0.5
aftB 4267018 p.Arg607Ser missense_variant 0.17
aftB 4267271 c.1566G>A synonymous_variant 0.14
aftB 4267647 p.Asp397Gly missense_variant 1.0
aftB 4269573 c.-737A>G upstream_gene_variant 0.14
aftB 4269594 c.-758A>C upstream_gene_variant 0.21
aftB 4269606 c.-770T>C upstream_gene_variant 0.19
aftB 4269612 c.-776T>C upstream_gene_variant 0.21
aftB 4269621 c.-785C>G upstream_gene_variant 0.21
ubiA 4269627 p.Val69Thr missense_variant 0.19
ubiA 4269632 p.Ala68Ser missense_variant 0.2
aftB 4269639 c.-803C>G upstream_gene_variant 0.2
ubiA 4269647 p.Ser63Cys missense_variant 0.23
aftB 4269660 c.-824C>T upstream_gene_variant 0.27
ubiA 4269665 p.Met57Val missense_variant 0.27
aftB 4269666 c.-830G>C upstream_gene_variant 0.3
whiB6 4338446 p.Leu26Met missense_variant 0.29
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407745 p.Ile153Thr missense_variant 0.17
gid 4407774 p.Asp143Glu missense_variant 0.18
gid 4407927 p.Glu92Asp missense_variant 1.0