TB-Profiler result

Run: SRR6045332
Summary

Run ID: SRR6045332

Sample name:

Date: 04-04-2023 11:57:08

Number of reads: 1536

Percentage reads mapped: 0.45

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 1.0 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoB 760946 c.1140A>G synonymous_variant 1.0
rpoC 765607 c.2238C>G synonymous_variant 1.0
rpoC 765611 p.His748Ala missense_variant 1.0
rpoC 765619 c.2250G>A synonymous_variant 1.0
rpoC 765625 c.2256C>T synonymous_variant 1.0
rpoC 765631 p.Asp754Glu missense_variant 1.0
rpoC 765676 c.2307G>A synonymous_variant 1.0
rpoC 765688 c.2319G>C synonymous_variant 1.0
rpoC 765694 c.2325G>C synonymous_variant 1.0
mmpL5 777563 c.918C>G synonymous_variant 0.67
mmpL5 777587 c.894G>C synonymous_variant 0.67
mmpL5 777593 c.888G>A synonymous_variant 0.67
mmpL5 777596 c.885G>A synonymous_variant 0.67
mmpL5 777605 c.876C>T synonymous_variant 0.67
rrs 1472164 n.319G>A non_coding_transcript_exon_variant 1.0
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 1.0
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 1.0
rrs 1472203 n.358G>A non_coding_transcript_exon_variant 1.0
rrs 1472210 n.365A>C non_coding_transcript_exon_variant 1.0
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 1.0
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 1.0
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 1.0
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 1.0
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 1.0
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 1.0
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 1.0
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 1.0
rrs 1473248 n.1403G>A non_coding_transcript_exon_variant 1.0
rrs 1473249 n.1404T>C non_coding_transcript_exon_variant 1.0
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 1.0
rrs 1473255 n.1410A>G non_coding_transcript_exon_variant 1.0
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 1.0
rrs 1473260 n.1415G>T non_coding_transcript_exon_variant 1.0
rrl 1474839 n.1182C>T non_coding_transcript_exon_variant 1.0
rrl 1474844 n.1187G>T non_coding_transcript_exon_variant 1.0
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.67
rrl 1474866 n.1209C>A non_coding_transcript_exon_variant 0.67
rrl 1474869 n.1212G>T non_coding_transcript_exon_variant 0.75
rrl 1474892 n.1235G>A non_coding_transcript_exon_variant 1.0
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 1.0
rrl 1474902 n.1245T>C non_coding_transcript_exon_variant 1.0
rrl 1474903 n.1246T>A non_coding_transcript_exon_variant 1.0
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 1.0
rrl 1474913 n.1256T>A non_coding_transcript_exon_variant 1.0
rrl 1474920 n.1263G>C non_coding_transcript_exon_variant 1.0
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 1.0
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0
rrl 1475713 n.2056C>G non_coding_transcript_exon_variant 1.0
rrl 1475716 n.2059A>G non_coding_transcript_exon_variant 1.0
rrl 1475751 n.2094C>G non_coding_transcript_exon_variant 1.0
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 1.0
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 1.0
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 1.0
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 1.0
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 1.0
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 1.0
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 1.0
rrl 1476108 n.2451T>C non_coding_transcript_exon_variant 1.0
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.67
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.67
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0
rrl 1476268 n.2611A>T non_coding_transcript_exon_variant 0.67
rrl 1476275 n.2618T>A non_coding_transcript_exon_variant 0.67
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.67
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.67
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.5
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.67
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.78
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.83
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.83
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.83
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.83
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.75
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.75
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.75
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.75
rrl 1476439 n.2782G>T non_coding_transcript_exon_variant 0.25
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.8
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 1.0
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 1.0