TB-Profiler result

Run: SRR6045572
Summary

Run ID: SRR6045572

Sample name:

Date: 04-04-2023 12:01:45

Number of reads: 2719952

Percentage reads mapped: 97.79

Strain: lineage4.6.3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
lineage4.6.3 Euro-American T;LAM None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8049 p.Ser250Ala missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
ccsA 620072 p.Pro61Leu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776987 c.1493delC frameshift_variant 1.0
mmpS5 778673 p.Pro78Leu missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.5
rrs 1472695 n.850C>T non_coding_transcript_exon_variant 0.33
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.14
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.17
rrs 1473089 n.1244A>C non_coding_transcript_exon_variant 0.21
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.14
rrs 1473099 n.1254T>C non_coding_transcript_exon_variant 0.15
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.15
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.15
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.14
rrs 1473107 n.1262G>A non_coding_transcript_exon_variant 0.14
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.14
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.14
rrs 1473120 n.1275C>T non_coding_transcript_exon_variant 0.13
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.13
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.13
rrs 1473132 n.1287T>C non_coding_transcript_exon_variant 0.13
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.13
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.67
rrl 1474253 n.596A>T non_coding_transcript_exon_variant 0.67
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.67
rrl 1474282 n.625G>T non_coding_transcript_exon_variant 0.67
rrl 1474287 n.630T>C non_coding_transcript_exon_variant 0.67
rrl 1474303 n.646A>T non_coding_transcript_exon_variant 0.67
rrl 1474306 n.649A>T non_coding_transcript_exon_variant 0.67
rrl 1474308 n.653_654delTG non_coding_transcript_exon_variant 0.67
rrl 1474315 n.658A>G non_coding_transcript_exon_variant 0.67
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 0.67
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.67
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.67
rrl 1475713 n.2056C>G non_coding_transcript_exon_variant 0.29
rrl 1475716 n.2059A>G non_coding_transcript_exon_variant 0.33
rrl 1475717 n.2060C>G non_coding_transcript_exon_variant 0.33
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.18
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.18
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.18
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.18
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.14
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.13
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.13
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.13
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.13
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.12
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.13
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.13
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.13
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.12
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.12
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.2
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.14
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.13
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.13
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.13
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.14
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.16
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.15
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2167876 c.2736dupC frameshift_variant 1.0
PPE35 2170066 p.Ala183Thr missense_variant 0.24
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ald 3086733 c.-87G>A upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
embC 4242185 p.Asp775Asn missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4268573 p.Met88Ile missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0