TB-Profiler result

Run: SRR6398010
Summary

Run ID: SRR6398010

Sample name:

Date: 04-04-2023 14:21:07

Number of reads: 4764912

Percentage reads mapped: 98.9

Strain: lineage4.2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.2 Euro-American H;T;LAM None 1.0
lineage4.2.1 Euro-American (TUR) H3;H4 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491247 c.465C>T synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.15
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.15
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.15
rrs 1472597 n.752G>A non_coding_transcript_exon_variant 0.12
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 0.2
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.22
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.18
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.18
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.18
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.2
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.19
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.19
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.19
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.19
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.19
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.19
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.16
rrl 1474634 n.977T>C non_coding_transcript_exon_variant 0.1
rrl 1474636 n.979A>C non_coding_transcript_exon_variant 0.15
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.16
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.17
rrl 1474709 n.1052G>A non_coding_transcript_exon_variant 0.12
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.15
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.19
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.15
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.15
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.15
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.25
rrl 1474883 n.1226T>C non_coding_transcript_exon_variant 0.17
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.17
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.13
rrl 1475722 n.2065G>T non_coding_transcript_exon_variant 0.15
rrl 1475751 n.2094C>T non_coding_transcript_exon_variant 0.19
rrl 1475752 n.2095C>T non_coding_transcript_exon_variant 0.18
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.19
rrl 1475758 n.2101A>G non_coding_transcript_exon_variant 0.19
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.18
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.17
rrl 1475869 n.2212C>A non_coding_transcript_exon_variant 0.12
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.12
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.12
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.16
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.18
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.19
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.17
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.18
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.16
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.11
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.11
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.11
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.13
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.11
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.12
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.11
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.11
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.1
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.11
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.11
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.11
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169879 p.Phe245Cys missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ald 3086742 c.-78A>C upstream_gene_variant 0.98
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878171 p.Pro113Ser missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4249594 c.3081G>A synonymous_variant 1.0
ethA 4328376 c.-903G>C upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0