TB-Profiler result

Run: SRR6650192
Summary

Run ID: SRR6650192

Sample name:

Date: 04-04-2023 15:18:37

Number of reads: 473666

Percentage reads mapped: 99.62

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5332 c.93C>T synonymous_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 8168 p.Glu289Asp missense_variant 1.0
rpoC 764431 c.1066delA frameshift_variant 0.17
rpoC 767033 p.Ser1222Ala missense_variant 0.67
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775734 p.Phe916Cys missense_variant 0.2
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1305303 c.2373T>G synonymous_variant 0.25
Rv1258c 1406462 c.879C>T synonymous_variant 0.22
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1475567 n.1910C>A non_coding_transcript_exon_variant 0.2
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2101721 p.Arg441Leu missense_variant 0.17
PPE35 2168149 p.Pro822Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2714887 p.Phe149Cys missense_variant 0.18
pepQ 2860072 p.Gly116Asp missense_variant 0.25
Rv2752c 3065126 p.Ser356Pro missense_variant 0.12
ald 3087714 p.Ala299Ser missense_variant 0.13
clpC1 4039729 p.Asp326Asn missense_variant 1.0
panD 4044356 c.-75T>C upstream_gene_variant 0.22
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4245010 p.Ala593Val missense_variant 0.4
embA 4245417 p.Gly729Arg missense_variant 1.0
embA 4246368 p.Leu1046Met missense_variant 0.25
embB 4246596 p.Trp28Leu missense_variant 0.17
embB 4248542 p.Ala677Ser missense_variant 0.22
embB 4249010 c.2497C>T synonymous_variant 0.15
aftB 4268568 p.Leu90Arg missense_variant 0.29
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407712 p.Gly164Asp missense_variant 1.0