TB-Profiler result

Run: SRR6785345
Summary

Run ID: SRR6785345

Sample name:

Date: 04-04-2023 15:48:03

Number of reads: 830757

Percentage reads mapped: 99.56

Strain: lineage4.2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.2 Euro-American H;T;LAM None 0.99
lineage4.2.1 Euro-American (TUR) H3;H4 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491247 c.465C>T synonymous_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.36
rpoB 760022 c.216T>G synonymous_variant 0.2
rpoC 764090 p.Tyr241Asn missense_variant 0.25
rpoC 765093 p.Ala575Val missense_variant 0.12
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1305056 p.Met709Thr missense_variant 0.1
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673346 c.-94C>G upstream_gene_variant 0.3
fabG1 1673349 c.-91G>C upstream_gene_variant 0.3
fabG1 1673380 c.-60C>G upstream_gene_variant 0.38
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170266 p.Gly116Asp missense_variant 1.0
PPE35 2170271 c.342T>C synonymous_variant 1.0
PPE35 2170308 p.Leu102Ala missense_variant 1.0
PPE35 2170313 c.300G>C synonymous_variant 1.0
Rv1979c 2222618 p.Trp183Arg missense_variant 0.2
Rv1979c 2222762 p.Ser135Cys missense_variant 0.17
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ribD 2986910 c.72C>A synonymous_variant 1.0
ald 3086742 c.-78A>C upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473998 c.-9G>A upstream_gene_variant 1.0
embC 4242186 p.Asp775Ala missense_variant 0.75
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4246483 p.Trp1084* stop_gained 0.2
embA 4246489 p.Arg1086Leu missense_variant 0.18
embB 4249594 c.3081G>A synonymous_variant 1.0
ethA 4328376 c.-903G>C upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0