Run ID: SRR6785387
Sample name:
Date: 04-04-2023 15:51:08
Number of reads: 2075573
Percentage reads mapped: 99.78
Strain: lineage4.3.3
Drug-resistance: Other
Drug | Resistance | Supporting mutations |
---|
Lineage | Family | Main Spoligotype | RDs | Frequency |
---|---|---|---|---|
lineage4 | Euro-American | LAM;T;S;X;H | None | 1.0 |
lineage4.3 | Euro-American (LAM) | mainly-LAM | None | 1.0 |
lineage4.3.3 | Euro-American (LAM) | LAM;T | RD115 | 1.0 |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
---|---|---|---|---|---|
ethA | 4326986 | c.487delC | frameshift_variant | 0.15 | ethionamide |
Gene | Chromosome position | Mutation | Type | Estimated fraction |
---|---|---|---|---|
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 |
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 |
gyrA | 8040 | p.Gly247Ser | missense_variant | 1.0 |
gyrA | 9249 | p.Ala650Ser | missense_variant | 0.35 |
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 |
rpoB | 759813 | p.Asp3Tyr | missense_variant | 0.17 |
rpoC | 764995 | c.1626C>G | synonymous_variant | 1.0 |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 |
mmpR5 | 779109 | p.Leu40Phe | missense_variant | 0.14 |
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 |
rrl | 1474173 | n.516T>C | non_coding_transcript_exon_variant | 0.29 |
rpsA | 1833881 | p.Gly114Cys | missense_variant | 0.14 |
rpsA | 1834836 | p.Met432Thr | missense_variant | 1.0 |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 |
ndh | 2102782 | c.260delG | frameshift_variant | 0.13 |
katG | 2156196 | c.-85C>T | upstream_gene_variant | 1.0 |
PPE35 | 2169381 | p.Trp411Thr | missense_variant | 0.17 |
PPE35 | 2169462 | p.Val384Ala | missense_variant | 0.13 |
PPE35 | 2170048 | p.Leu189Val | missense_variant | 0.47 |
PPE35 | 2170053 | p.Thr187Ser | missense_variant | 0.44 |
PPE35 | 2170447 | p.Ser56Ala | missense_variant | 0.25 |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 |
kasA | 2518919 | p.Gly269Ser | missense_variant | 1.0 |
folC | 2746340 | p.Ala420Val | missense_variant | 1.0 |
thyA | 3073868 | p.Thr202Ala | missense_variant | 1.0 |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 |
fprA | 3473996 | c.-11_-10insA | upstream_gene_variant | 1.0 |
clpC1 | 4038287 | c.2418C>T | synonymous_variant | 1.0 |
clpC1 | 4038968 | c.1737G>A | synonymous_variant | 1.0 |
embA | 4242406 | c.-827A>C | upstream_gene_variant | 0.17 |
embA | 4242643 | c.-590C>T | upstream_gene_variant | 1.0 |
embA | 4245467 | c.2235C>G | synonymous_variant | 0.1 |
embB | 4246548 | p.Pro12Gln | missense_variant | 0.43 |
embB | 4246555 | c.42G>C | synonymous_variant | 0.5 |
embB | 4246556 | p.Ala15Pro | missense_variant | 0.5 |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 |
gid | 4408156 | p.Leu16Arg | missense_variant | 1.0 |