Run ID: SRR6824328
Sample name:
Date: 04-04-2023 16:27:26
Number of reads: 9781552
Percentage reads mapped: 99.17
Strain: lineage4.5
Drug-resistance: MDR-TB
Drug | Resistance | Supporting mutations |
---|
Lineage | Family | Main Spoligotype | RDs | Frequency |
---|---|---|---|---|
lineage4 | Euro-American | LAM;T;S;X;H | None | 1.0 |
lineage4.5 | Euro-American | H;T | RD122 | 1.0 |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
---|---|---|---|---|---|
rpoB | 761139 | p.His445Tyr | missense_variant | 1.0 | rifampicin |
rrs | 1472751 | n.906A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin |
katG | 2155168 | p.Ser315Thr | missense_variant | 1.0 | isoniazid |
Gene | Chromosome position | Mutation | Type | Estimated fraction |
---|---|---|---|---|
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 |
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 |
gyrA | 7892 | c.591G>A | synonymous_variant | 1.0 |
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 |
ccsA | 620029 | c.139C>T | synonymous_variant | 1.0 |
rpoC | 765867 | p.Pro833Leu | missense_variant | 1.0 |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 |
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 |
rrs | 1473097 | n.1252G>A | non_coding_transcript_exon_variant | 0.11 |
rrs | 1473100 | n.1255G>A | non_coding_transcript_exon_variant | 0.1 |
rrs | 1473110 | n.1265T>G | non_coding_transcript_exon_variant | 0.1 |
rrs | 1473111 | n.1266A>G | non_coding_transcript_exon_variant | 0.1 |
rrs | 1473121 | n.1276T>C | non_coding_transcript_exon_variant | 0.1 |
rrs | 1473122 | n.1277T>A | non_coding_transcript_exon_variant | 0.11 |
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.1 |
rrl | 1476200 | n.2543A>T | non_coding_transcript_exon_variant | 0.1 |
rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 0.11 |
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.12 |
rrl | 1476245 | n.2588C>T | non_coding_transcript_exon_variant | 0.11 |
rrl | 1476252 | n.2595T>G | non_coding_transcript_exon_variant | 0.11 |
rrl | 1476260 | n.2603A>G | non_coding_transcript_exon_variant | 0.11 |
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.1 |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 |
PPE35 | 2170568 | p.Ile15Met | missense_variant | 1.0 |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 |
fprA | 3473996 | c.-11_-10insA | upstream_gene_variant | 1.0 |
alr | 3841431 | c.-11A>C | upstream_gene_variant | 0.17 |
rpoA | 3878575 | c.-68C>T | upstream_gene_variant | 1.0 |
clpC1 | 4038318 | p.Pro796Leu | missense_variant | 1.0 |
embA | 4242643 | c.-590C>T | upstream_gene_variant | 1.0 |
embA | 4243813 | p.Arg194Gln | missense_variant | 1.0 |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 |