TB-Profiler result

Run: SRR6832825
Summary

Run ID: SRR6832825

Sample name:

Date: 04-04-2023 17:40:02

Number of reads: 2014463

Percentage reads mapped: 98.77

Strain: lineage4.3.3;lineage4.1.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 0.07
lineage4.1 Euro-American T;X;H None 0.94
lineage4.1.2 Euro-American T;H None 0.91
lineage4.3.3 Euro-American (LAM) LAM;T RD115 0.07
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491591 p.Lys270Met missense_variant 0.96
rpoB 760115 c.309C>T synonymous_variant 0.97
rpoC 764263 c.894G>A synonymous_variant 1.0
rpoC 764995 c.1626C>G synonymous_variant 0.12
rpoC 765150 p.Gly594Glu missense_variant 0.97
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777320 c.1161C>G synonymous_variant 0.88
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918584 c.645A>C synonymous_variant 0.85
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518076 c.-39C>T upstream_gene_variant 0.81
kasA 2518919 p.Gly269Ser missense_variant 0.19
thyA 3073868 p.Thr202Ala missense_variant 0.11
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3611974 c.1143A>C synonymous_variant 0.85
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 0.86
embA 4245385 p.Thr718Ile missense_variant 0.86
embB 4248365 p.Val618Met missense_variant 0.9
whiB6 4338595 c.-75delG upstream_gene_variant 1.0