TB-Profiler result

Run: SRR6855897
Summary

Run ID: SRR6855897

Sample name:

Date: 04-04-2023 17:49:22

Number of reads: 328846

Percentage reads mapped: 99.59

Strain: lineage4.1.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.2 Euro-American T;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
ccsA 620371 c.485delC frameshift_variant 0.12
rpoB 759693 c.-114C>A upstream_gene_variant 0.12
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303344 p.Phe138Leu missense_variant 0.15
fbiC 1304880 c.1950C>G synonymous_variant 0.12
embR 1416305 p.Asn348Ser missense_variant 0.11
embR 1416342 p.Gly336Cys missense_variant 0.11
embR 1416809 p.Ala180Val missense_variant 0.1
embR 1417140 p.Ala70Ser missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673249 c.-191C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2101763 p.Gly427Asp missense_variant 0.11
katG 2154796 p.Gln439Arg missense_variant 0.18
katG 2155705 p.Pro136Leu missense_variant 0.13
katG 2155912 p.Glu67Val missense_variant 0.14
PPE35 2168139 p.Ala825Val missense_variant 0.14
PPE35 2169895 p.Gly240Ser missense_variant 0.17
PPE35 2169910 p.Asn235Asp missense_variant 0.15
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2747022 p.Val193Ile missense_variant 1.0
thyX 3067193 c.753A>G stop_lost&splice_region_variant 0.12
thyX 3067654 p.His98Tyr missense_variant 0.13
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3448894 p.Tyr131Asp missense_variant 1.0
Rv3083 3449642 p.Asn380Ser missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568466 p.Asp72Tyr missense_variant 0.18
fbiA 3641026 p.Glu162Lys missense_variant 0.15
fbiA 3641164 p.Ile208Val missense_variant 1.0
fbiA 3641195 p.Val218Ala missense_variant 0.13
alr 3840390 p.Asp344Gly missense_variant 0.1
clpC1 4039182 p.Leu508Ser missense_variant 0.12
panD 4044149 p.Thr45Ala missense_variant 0.17
embC 4240030 c.168C>G synonymous_variant 0.12
embC 4240182 p.Ser107Leu missense_variant 0.12
embC 4240669 c.808dupA frameshift_variant 0.1
embC 4241995 c.2134delA frameshift_variant 0.17
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4245932 c.-582C>A upstream_gene_variant 0.25
embB 4247756 c.1245delC frameshift_variant 0.13
embB 4247838 p.Leu442Pro missense_variant 0.11
aftB 4268861 c.-25T>C upstream_gene_variant 0.92
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407934 p.Leu90Pro missense_variant 0.1