TB-Profiler result

Run: SRR6964570

Summary

Run ID: SRR6964570

Sample name:

Date: 04-04-2023 18:17:22

Number of reads: 417642

Percentage reads mapped: 99.44

Strain:

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 490855 p.Val25Ile missense_variant 0.18
fgd1 491742 c.960T>C synonymous_variant 1.0
rpoB 759746 c.-61C>T upstream_gene_variant 1.0
rpoB 760141 p.Pro112Leu missense_variant 0.15
rpoB 762013 p.Val736Ala missense_variant 0.14
rpoC 762434 c.-936T>G upstream_gene_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 767316 p.Arg1316His missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776591 c.1890C>A synonymous_variant 0.17
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781769 c.210G>A synonymous_variant 0.22
Rv1258c 1406726 c.615C>T synonymous_variant 0.33
embR 1416454 c.894T>C synonymous_variant 0.25
embR 1416757 c.591G>A synonymous_variant 0.2
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472482 n.637G>A non_coding_transcript_exon_variant 0.25
rrl 1474659 n.1002T>C non_coding_transcript_exon_variant 0.22
fabG1 1673503 p.Gly22Arg missense_variant 0.29
rpsA 1834856 p.Glu439Lys missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2169844 p.Ile257Val missense_variant 0.82
PPE35 2170048 p.Leu189Val missense_variant 0.82
PPE35 2170053 p.Thr187Ser missense_variant 0.82
PPE35 2170066 p.Ala183Thr missense_variant 0.25
Rv1979c 2222231 p.Met312Leu missense_variant 0.22
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2288950 p.Ala98Ser missense_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 1.0
kasA 2518375 c.261C>T synonymous_variant 0.17
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
pepQ 2859944 p.Ala159Thr missense_variant 0.22
pepQ 2860431 c.-13A>G upstream_gene_variant 0.25
Rv2752c 3065588 p.Asp202Asn missense_variant 0.33
Rv2752c 3066996 c.-805T>C upstream_gene_variant 0.29
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474726 c.720G>A synonymous_variant 1.0
whiB7 3568746 c.-67G>A upstream_gene_variant 1.0
fbiB 3641841 p.Gln103Lys missense_variant 0.18
alr 3841488 c.-68C>T upstream_gene_variant 0.17
ddn 3986818 c.-26G>T upstream_gene_variant 1.0
clpC1 4038851 c.1854G>A synonymous_variant 0.11
embC 4242075 p.Arg738Gln missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246548 p.Pro12Gln missense_variant 0.17
embB 4246555 c.42G>C synonymous_variant 0.17
embB 4246556 p.Ala15Pro missense_variant 0.17
aftB 4267240 p.Phe533Ile missense_variant 0.5
ubiA 4269905 c.-72G>A upstream_gene_variant 0.25
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4408023 p.Glu60Asp missense_variant 1.0