TB-Profiler result

Run: SRR6982259
Summary

Run ID: SRR6982259

Sample name:

Date: 04-04-2023 18:32:02

Number of reads: 881660

Percentage reads mapped: 98.84

Strain: lineage4.8.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 0.82
lineage4.8.1 Euro-American (mainly T) T1;T2;T3;T5 RD219 0.83
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 0.11
gyrA 9304 p.Gly668Asp missense_variant 0.18
ccsA 620625 p.Ile245Met missense_variant 0.21
rpoC 763708 c.339G>A synonymous_variant 0.1
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.69
rrl 1476056 n.2399G>A non_coding_transcript_exon_variant 0.17
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 0.14
PPE35 2168149 p.Pro822Ser missense_variant 0.78
PPE35 2170101 p.Pro171Leu missense_variant 0.12
Rv1979c 2223051 p.Glu38Asp missense_variant 0.12
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
thyA 3073868 p.Thr202Ala missense_variant 0.18
ald 3086788 c.-32T>C upstream_gene_variant 0.32
fbiD 3339040 c.-78T>C upstream_gene_variant 0.9
fprA 3473996 c.-11_-10insA upstream_gene_variant 0.1
fbiB 3642874 p.Leu447Arg missense_variant 0.74
embC 4241925 p.Arg688Leu missense_variant 0.13
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4268468 c.369G>T synonymous_variant 0.11
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 0.12