TB-Profiler result

Run: SRR7131148
Summary

Run ID: SRR7131148

Sample name:

Date: 04-04-2023 18:46:53

Number of reads: 949050

Percentage reads mapped: 99.99

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.17
mshA 576482 p.Val379Leu missense_variant 0.25
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.11
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.1
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474126 n.469G>A non_coding_transcript_exon_variant 0.12
rrl 1474611 n.954A>T non_coding_transcript_exon_variant 0.11
rrl 1474880 n.1223T>A non_coding_transcript_exon_variant 0.11
rrl 1475262 n.1605G>T non_coding_transcript_exon_variant 0.1
rrl 1475610 n.1953G>T non_coding_transcript_exon_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102722 c.321C>A synonymous_variant 0.11
PPE35 2168149 p.Pro822Ser missense_variant 1.0
PPE35 2169168 p.Leu482* stop_gained 0.18
PPE35 2169628 p.Ile329Val missense_variant 0.13
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ald 3086999 c.180C>G synonymous_variant 1.0
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
clpC1 4039729 p.Asp326Asn missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246544 p.Thr11Pro missense_variant 0.25
ethA 4327461 p.Leu5Phe missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0