TB-Profiler result

Run: SRR7131166
Summary

Run ID: SRR7131166

Sample name:

Date: 04-04-2023 18:47:34

Number of reads: 1347072

Percentage reads mapped: 99.99

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 9539 c.2238C>T synonymous_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.17
mshA 576482 p.Val379Leu missense_variant 0.17
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 778092 p.Trp130Leu missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471868 n.23T>C non_coding_transcript_exon_variant 0.1
rrs 1472587 n.742T>C non_coding_transcript_exon_variant 0.2
rrl 1473665 n.8T>C non_coding_transcript_exon_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170047 p.Leu189Arg missense_variant 0.15
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.17
alr 3841080 p.His114Pro missense_variant 1.0
embB 4246584 p.Arg24Pro missense_variant 1.0
embB 4246694 c.186delG frameshift_variant 0.1
aftB 4268684 c.152delA frameshift_variant 0.1
whiB6 4338473 c.49A>C synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0