TB-Profiler result

Run: SRR8692759
Summary

Run ID: SRR8692759

Sample name:

Date: 13-08-2023 18:50:54

Number of reads: NA

Percentage reads mapped: NA

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rplC 801268 p.Cys154Arg missense_variant 0.97 linezolid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
mmpL5 776766 p.Ala572Val missense_variant 0.11
Rv1258c 1406686 p.Val219Ile missense_variant 0.95
atpE 1460985 c.-60G>T upstream_gene_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471781 n.-65G>T upstream_gene_variant 0.25
rrs 1471823 n.-23C>A upstream_gene_variant 0.2
rrs 1471946 n.101C>A non_coding_transcript_exon_variant 0.2
rrs 1471979 n.134T>C non_coding_transcript_exon_variant 0.2
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.2
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.2
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.2
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.22
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.22
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.13
rrs 1472447 n.602C>A non_coding_transcript_exon_variant 0.18
rrl 1473676 n.19G>A non_coding_transcript_exon_variant 0.17
rrl 1473763 n.106C>A non_coding_transcript_exon_variant 0.17
rrl 1474093 n.436G>T non_coding_transcript_exon_variant 0.5
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.27
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.27
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.25
rrl 1474498 n.841G>A non_coding_transcript_exon_variant 0.25
rrl 1474505 n.848C>T non_coding_transcript_exon_variant 0.25
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.21
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.21
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.21
rrl 1474524 n.867C>A non_coding_transcript_exon_variant 0.13
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.2
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.25
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.25
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.29
rrl 1474709 n.1053delT non_coding_transcript_exon_variant 0.25
rrl 1474714 n.1058delT non_coding_transcript_exon_variant 0.22
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.25
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.22
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.18
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.17
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.17
rrl 1475028 n.1371G>T non_coding_transcript_exon_variant 0.2
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 0.25
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.33
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.33
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.33
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.38
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.38
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.38
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.38
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.33
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.33
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.33
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.38
rrl 1476056 n.2399G>A non_coding_transcript_exon_variant 0.38
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.4
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.4
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.33
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.33
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.33
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.33
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.33
rrl 1476218 n.2561G>T non_coding_transcript_exon_variant 0.5
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.17
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 0.2
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.19
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.21
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.18
clpC1 4038617 p.Lys696Asn missense_variant 0.29
clpC1 4038667 p.Gly680Cys missense_variant 0.2
embC 4242031 c.2169G>T synonymous_variant 0.13
whiB6 4338668 c.-147G>T upstream_gene_variant 0.12