TB-Profiler result

Run: SRR8692828
Summary

Run ID: SRR8692828

Sample name:

Date: 13-08-2023 21:05:35

Number of reads: NA

Percentage reads mapped: NA

Strain: lineage4.9

Drug-resistance: Other

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rplC 801268 p.Cys154Arg missense_variant 0.99 linezolid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoB 761015 c.1209G>C synonymous_variant 0.1
rpoB 761036 c.1230G>C synonymous_variant 0.11
rpoB 761037 c.1231T>C synonymous_variant 0.11
Rv1258c 1406686 p.Val219Ile missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472549 n.704G>T non_coding_transcript_exon_variant 0.2
rrs 1472605 n.760G>T non_coding_transcript_exon_variant 0.14
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.18
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.18
rrl 1473971 n.314G>T non_coding_transcript_exon_variant 0.18
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.12
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.17
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.17
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.24
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 0.1
rrl 1475108 n.1451C>G non_coding_transcript_exon_variant 0.11
rrl 1475299 n.1642G>T non_coding_transcript_exon_variant 0.17
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.22
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.4
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.4
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.5
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 0.67
rrl 1475480 n.1823A>T non_coding_transcript_exon_variant 0.67
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.67
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.67
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.67
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.33
rrl 1475759 n.2102C>T non_coding_transcript_exon_variant 0.29
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.33
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.29
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.29
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.29
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 0.29
rrl 1475863 n.2206G>A non_coding_transcript_exon_variant 0.2
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.29
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.33
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.4
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.44
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.4
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.4
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.36
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.18
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.23
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.23
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.25
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 0.25
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.25
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.23
rrl 1476668 n.3011C>A non_coding_transcript_exon_variant 0.22
rpsA 1833676 c.135A>G synonymous_variant 0.15
rpsA 1833679 c.138G>C synonymous_variant 0.19
rpsA 1833685 c.144G>T synonymous_variant 0.16
rpsA 1833694 c.153G>T synonymous_variant 0.17
rpsA 1833697 c.156C>G synonymous_variant 0.16
rpsA 1833703 c.162C>T synonymous_variant 0.14
rpsA 1833709 c.168C>T synonymous_variant 0.13
rpsA 1833745 c.204G>C synonymous_variant 0.11