TB-Profiler result

Run: SRR8692899
Summary

Run ID: SRR8692899

Sample name:

Date: 13-08-2023 22:51:33

Number of reads: NA

Percentage reads mapped: NA

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rplC 801268 p.Cys154Arg missense_variant 0.94 linezolid
ethA 4326715 p.Cys253* stop_gained 0.25 ethionamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5743 c.504G>T synonymous_variant 0.27
gyrB 5857 c.618C>A synonymous_variant 0.14
gyrA 6478 c.-824G>T upstream_gene_variant 0.5
gyrA 7018 c.-284G>A upstream_gene_variant 0.2
gyrB 7113 p.Thr625Ile missense_variant 0.22
gyrA 8155 p.Thr285Asn missense_variant 0.12
gyrA 8172 p.Val291Ile missense_variant 0.12
gyrA 8231 c.930C>A synonymous_variant 0.18
gyrA 8817 p.Ser506Gly missense_variant 0.29
fgd1 491022 c.240C>G synonymous_variant 0.13
fgd1 491031 c.249C>G synonymous_variant 0.12
fgd1 491043 c.261T>C synonymous_variant 0.13
fgd1 491049 c.267T>G synonymous_variant 0.13
fgd1 491064 c.282A>C synonymous_variant 0.13
fgd1 491077 p.Asn99Asp missense_variant 0.12
fgd1 491082 c.300T>G synonymous_variant 0.12
fgd1 491083 p.Val101Ile missense_variant 0.12
fgd1 491091 c.309T>G synonymous_variant 0.12
fgd1 491095 p.Val105Ile missense_variant 0.13
fgd1 491106 c.324T>C synonymous_variant 0.13
fgd1 491115 c.333G>C synonymous_variant 0.13
fgd1 491121 c.339A>G synonymous_variant 0.13
fgd1 491133 c.351A>C synonymous_variant 0.13
fgd1 491144 p.Ala121Asp missense_variant 0.14
mshA 575265 c.-83C>A upstream_gene_variant 0.14
mshA 575286 c.-62G>T upstream_gene_variant 0.14
mshA 576170 p.Gln275Lys missense_variant 0.17
ccsA 619886 c.-5G>T upstream_gene_variant 0.17
ccsA 619924 p.Arg12Gly missense_variant 0.17
ccsA 620134 p.Ala82Pro missense_variant 0.18
ccsA 620550 c.660C>A synonymous_variant 0.25
rpoB 759721 c.-86G>T upstream_gene_variant 0.2
rpoB 759735 c.-72G>T upstream_gene_variant 0.2
rpoB 759770 c.-37C>A upstream_gene_variant 0.18
rpoB 760235 c.429T>C synonymous_variant 0.17
rpoB 760244 c.438G>C synonymous_variant 0.18
rpoB 760256 c.450C>T synonymous_variant 0.15
rpoB 760260 p.Pro152Thr missense_variant 0.15
rpoB 760333 p.Ser176* stop_gained 0.15
rpoB 760445 c.639C>A synonymous_variant 0.4
rpoB 760635 p.Pro277Thr missense_variant 0.22
rpoB 760796 c.990A>G synonymous_variant 0.33
rpoB 760805 c.999G>C synonymous_variant 0.27
rpoB 760808 c.1002C>G synonymous_variant 0.27
rpoB 760811 c.1005C>G synonymous_variant 0.25
rpoB 760817 c.1011A>G synonymous_variant 0.25
rpoB 760820 c.1014T>C synonymous_variant 0.25
rpoB 760826 c.1020C>G synonymous_variant 0.3
rpoB 760830 c.1024T>C synonymous_variant 0.3
rpoB 760841 c.1035T>C synonymous_variant 0.3
rpoB 760858 p.Val351Ala missense_variant 0.3
rpoB 760862 c.1056G>C synonymous_variant 0.3
rpoB 760877 c.1071G>T synonymous_variant 0.27
rpoB 760880 c.1074G>C synonymous_variant 0.27
rpoB 760883 c.1077G>C synonymous_variant 0.27
rpoB 760886 c.1080A>G synonymous_variant 0.27
rpoB 760887 p.Thr361Val missense_variant 0.3
rpoB 760910 c.1104C>T synonymous_variant 0.38
rpoB 760919 c.1113C>T synonymous_variant 0.38
rpoB 760925 c.1119T>C synonymous_variant 0.38
rpoB 760928 c.1122G>C synonymous_variant 0.33
rpoB 761015 c.1209G>C synonymous_variant 0.4
rpoB 761027 c.1221A>C synonymous_variant 0.67
rpoB 761036 c.1230G>C synonymous_variant 0.5
rpoB 761037 c.1231T>C synonymous_variant 0.5
rpoB 761051 c.1245G>T synonymous_variant 0.5
rpoB 761054 c.1248G>C synonymous_variant 0.5
rpoB 761057 c.1251G>C synonymous_variant 0.5
rpoB 761060 c.1254C>G synonymous_variant 0.5
rpoB 761063 c.1257C>G synonymous_variant 0.5
rpoB 761370 p.Ile522Val missense_variant 0.5
rpoB 761813 c.2007T>C synonymous_variant 0.2
rpoB 761834 c.2028T>C synonymous_variant 0.17
rpoB 761847 p.Cys681Arg missense_variant 0.15
rpoB 761852 c.2046C>G synonymous_variant 0.15
rpoB 761862 p.Ala686Thr missense_variant 0.14
rpoB 761867 c.2061C>A synonymous_variant 0.14
rpoB 761868 p.Asp688Gln missense_variant 0.14
rpoB 761873 c.2067A>G synonymous_variant 0.14
rpoB 761876 c.2070C>G synonymous_variant 0.15
rpoB 761892 p.Ile696Leu missense_variant 0.15
rpoB 761903 c.2097T>C synonymous_variant 0.14
rpoB 761909 c.2103T>C synonymous_variant 0.15
rpoB 761912 c.2106T>C synonymous_variant 0.17
rpoB 761915 p.Asp703Glu missense_variant 0.18
rpoB 761916 p.Asp704Asn missense_variant 0.18
rpoB 761921 c.2115C>T synonymous_variant 0.18
rpoB 761930 c.2124G>C synonymous_variant 0.22
rpoB 762080 c.2274G>C synonymous_variant 0.12
rpoB 762144 p.Glu780* stop_gained 0.17
rpoB 762160 p.Arg785Leu missense_variant 0.14
rpoB 762200 c.2394C>T synonymous_variant 0.18
rpoB 762218 c.2412T>C synonymous_variant 0.18
rpoB 762233 c.2427G>C synonymous_variant 0.15
rpoB 762245 c.2439G>C synonymous_variant 0.17
rpoB 762332 c.2526C>T synonymous_variant 0.18
rpoB 762520 p.Thr905Ile missense_variant 0.15
rpoB 762633 p.Ala943Ser missense_variant 0.22
rpoB 762730 p.Gln975Arg missense_variant 0.18
rpoC 763486 c.117T>C synonymous_variant 0.22
rpoC 763495 c.126G>A synonymous_variant 0.22
rpoC 763573 c.204G>C synonymous_variant 0.17
rpoC 763594 c.225C>T synonymous_variant 0.15
rpoC 764737 c.1368G>T synonymous_variant 0.22
rpoC 765528 p.Gly720Val missense_variant 0.18
rpoC 765933 p.Gly855Val missense_variant 0.12
rpoC 765937 c.2568T>C synonymous_variant 0.13
rpoC 765940 c.2571A>T synonymous_variant 0.14
rpoC 765946 c.2577C>T synonymous_variant 0.15
rpoC 765947 c.2578T>C synonymous_variant 0.15
rpoC 765952 c.2583G>C synonymous_variant 0.17
rpoC 765962 c.2593T>C synonymous_variant 0.2
rpoC 765967 c.2598C>T synonymous_variant 0.2
rpoC 765979 c.2610C>G synonymous_variant 0.2
rpoC 765982 c.2613C>T synonymous_variant 0.2
rpoC 765994 c.2625A>T synonymous_variant 0.17
rpoC 766102 c.2733C>A synonymous_variant 0.17
rpoC 766318 p.Met983Ile missense_variant 0.17
rpoC 766722 p.Pro1118Gln missense_variant 0.17
rpoC 766737 p.Arg1123Leu missense_variant 0.15
rpoC 766745 p.Gly1126Cys missense_variant 0.14
rpoC 766889 p.Glu1174* stop_gained 0.17
rpoC 766928 p.Glu1187* stop_gained 0.15
rpoC 766965 p.Glu1199Gly missense_variant 0.18
rpoC 766983 p.Pro1205Gln missense_variant 0.22
mmpL5 775981 p.Leu834Met missense_variant 0.15
mmpL5 775990 c.2491C>T synonymous_variant 0.15
mmpL5 778311 p.Gly57Val missense_variant 0.14
mmpL5 778383 p.Val33Ala missense_variant 0.12
mmpR5 778475 c.-515G>T upstream_gene_variant 0.17
mmpL5 778950 c.-470C>T upstream_gene_variant 0.22
mmpL5 779448 c.-968G>T upstream_gene_variant 0.25
rpsL 781404 c.-156G>T upstream_gene_variant 0.17
rpsL 781815 c.256C>A synonymous_variant 0.2
rpsL 781829 c.270G>C synonymous_variant 0.18
rpsL 781832 c.273T>G synonymous_variant 0.18
rpsL 781859 c.300T>C synonymous_variant 0.25
rpsL 781868 c.309T>C synonymous_variant 0.22
rpsL 781871 c.312G>C synonymous_variant 0.25
rpsL 781892 c.333A>G synonymous_variant 0.22
rpsL 781901 c.342C>T synonymous_variant 0.22
rpsL 781916 c.357T>G synonymous_variant 0.25
rplC 800717 c.-92C>A upstream_gene_variant 0.15
rplC 800725 c.-84C>T upstream_gene_variant 0.14
rplC 801196 p.His130Asp missense_variant 0.15
rplC 801353 p.Val182Ala missense_variant 0.17
fbiC 1303346 p.Gly139Asp missense_variant 0.17
fbiC 1303417 p.Gly163Cys missense_variant 0.22
fbiC 1304520 c.1590A>G synonymous_variant 0.22
fbiC 1304526 c.1596T>G synonymous_variant 0.33
fbiC 1304533 c.1603T>C synonymous_variant 0.33
fbiC 1304544 p.Asp538Glu missense_variant 0.38
fbiC 1304547 c.1617C>G synonymous_variant 0.38
fbiC 1304556 p.Asp542Glu missense_variant 0.33
fbiC 1304559 p.Glu543Asp missense_variant 0.38
fbiC 1304562 c.1632G>C synonymous_variant 0.38
fbiC 1304567 p.Phe546Tyr missense_variant 0.38
fbiC 1304571 c.1641G>C synonymous_variant 0.44
fbiC 1304580 c.1650T>C synonymous_variant 0.3
fbiC 1304613 c.1683T>C synonymous_variant 0.25
fbiC 1304634 c.1704C>G synonymous_variant 0.18
fbiC 1304640 c.1710A>C synonymous_variant 0.17
fbiC 1304646 c.1716T>C synonymous_variant 0.15
fbiC 1304663 p.Ser578Leu missense_variant 0.14
fbiC 1304850 c.1920C>T synonymous_variant 0.33
fbiC 1305051 c.2121G>C synonymous_variant 0.25
Rv1258c 1406273 c.1068C>T synonymous_variant 0.15
Rv1258c 1406626 p.Tyr239His missense_variant 0.25
Rv1258c 1406647 p.Asp232Tyr missense_variant 0.33
Rv1258c 1406686 p.Val219Ile missense_variant 0.5
Rv1258c 1407378 c.-38C>A upstream_gene_variant 0.29
embR 1416416 p.Gly311Val missense_variant 0.2
embR 1417029 p.Asp107Tyr missense_variant 0.18
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471979 n.134T>C non_coding_transcript_exon_variant 0.5
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.5
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 0.5
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 0.5
rrs 1472029 n.184C>T non_coding_transcript_exon_variant 0.57
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.57
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 0.5
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 0.44
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.44
rrs 1472043 n.198T>G non_coding_transcript_exon_variant 0.44
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.44
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.4
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.27
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.3
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.22
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.15
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.23
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.27
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.44
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.55
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.43
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.43
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.43
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 0.43
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.5
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.5
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 0.5
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.5
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.44
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.44
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.38
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.38
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.38
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.38
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.38
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.43
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.43
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.6
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.55
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.6
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.2
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.45
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.27
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.33
rrl 1473814 n.157A>C non_coding_transcript_exon_variant 0.3
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 0.3
rrl 1473816 n.159C>G non_coding_transcript_exon_variant 0.3
rrl 1473828 n.171G>C non_coding_transcript_exon_variant 0.3
rrl 1473829 n.172G>C non_coding_transcript_exon_variant 0.3
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 0.3
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 0.3
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.23
rrl 1473942 n.285G>T non_coding_transcript_exon_variant 0.22
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.29
rrl 1474408 n.751G>T non_coding_transcript_exon_variant 0.2
rrl 1474437 n.780G>T non_coding_transcript_exon_variant 0.2
rrl 1474449 n.792G>T non_coding_transcript_exon_variant 0.17
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.43
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.38
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.38
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.38
rrl 1474709 n.1053delT non_coding_transcript_exon_variant 0.33
rrl 1474714 n.1058delT non_coding_transcript_exon_variant 0.38
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.38
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.38
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.5
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.33
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.29
rrl 1475108 n.1451C>G non_coding_transcript_exon_variant 1.0
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 0.4
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.33
rrl 1475380 n.1723C>A non_coding_transcript_exon_variant 0.33
rrl 1475381 n.1724G>T non_coding_transcript_exon_variant 0.33
rrl 1475382 n.1725A>C non_coding_transcript_exon_variant 0.33
rrl 1475395 n.1738T>G non_coding_transcript_exon_variant 0.33
rrl 1475396 n.1739C>G non_coding_transcript_exon_variant 0.33
rrl 1475397 n.1740G>T non_coding_transcript_exon_variant 0.33
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.29
rrl 1475417 n.1760G>T non_coding_transcript_exon_variant 0.29
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.29
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.38
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.4
rrl 1475454 n.1797G>T non_coding_transcript_exon_variant 0.2
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.33
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 0.3
rrl 1475480 n.1823A>T non_coding_transcript_exon_variant 0.3
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.3
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.67
rrl 1475759 n.2102C>T non_coding_transcript_exon_variant 0.67
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.71
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.71
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.71
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.71
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 0.62
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.15
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.17
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.17
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.5
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.5
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.71
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.71
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.71
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.71
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.67
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.8
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.8
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.5
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 0.5
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.5
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.5
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.5
inhA 1674756 c.555T>C synonymous_variant 0.18
inhA 1674759 c.558G>T synonymous_variant 0.18
rpsA 1833425 c.-117C>A upstream_gene_variant 0.25
rpsA 1833691 p.Glu50Asp missense_variant 0.15
rpsA 1833787 c.246C>G synonymous_variant 0.22
rpsA 1833790 c.249T>C synonymous_variant 0.2
rpsA 1833793 c.252C>T synonymous_variant 0.2
rpsA 1833802 c.261A>G synonymous_variant 0.18
rpsA 1833808 c.267G>C synonymous_variant 0.25
rpsA 1833811 c.270G>T synonymous_variant 0.22
rpsA 1833829 c.288A>G synonymous_variant 0.2
rpsA 1833832 c.291G>A synonymous_variant 0.2
rpsA 1833838 c.297G>C synonymous_variant 0.2
rpsA 1833841 c.300C>G synonymous_variant 0.2
rpsA 1833847 c.306C>G synonymous_variant 0.18
rpsA 1833856 c.315A>G synonymous_variant 0.31
rpsA 1833862 c.321G>T synonymous_variant 0.38
rpsA 1833892 c.351G>A synonymous_variant 0.31
rpsA 1833894 p.Ala118Glu missense_variant 0.29
rpsA 1833928 c.387G>C synonymous_variant 0.2
rpsA 1833970 c.429G>C synonymous_variant 0.27
rpsA 1833976 c.435C>T synonymous_variant 0.36
rpsA 1833979 c.438T>C synonymous_variant 0.33
rpsA 1833991 c.450C>A synonymous_variant 0.36
rpsA 1834000 c.459G>C synonymous_variant 0.4
rpsA 1834487 p.Gly316Cys missense_variant 0.13
rpsA 1834623 p.Ser361* stop_gained 0.2
rpsA 1834901 p.Ala454Pro missense_variant 0.33
katG 2154417 c.1695G>T synonymous_variant 0.18
katG 2154464 p.Ala550Ser missense_variant 0.2
katG 2154480 c.1632C>A synonymous_variant 0.18
katG 2155434 c.678G>A synonymous_variant 0.15
katG 2156162 c.-51G>T upstream_gene_variant 0.15
PPE35 2167926 p.Leu896Ser missense_variant 0.12
PPE35 2168240 c.2373C>A synonymous_variant 0.2
PPE35 2168280 p.Pro778Gln missense_variant 0.17
PPE35 2168540 c.2073C>T synonymous_variant 0.33
PPE35 2168593 p.Pro674Thr missense_variant 0.67
PPE35 2170504 p.Glu37* stop_gained 0.18
Rv1979c 2223267 c.-103T>C upstream_gene_variant 0.2
Rv1979c 2223323 c.-159T>C upstream_gene_variant 0.17
pncA 2289221 c.21C>A synonymous_variant 0.17
pncA 2289431 c.-190G>A upstream_gene_variant 0.29
pncA 2289752 c.-511G>A upstream_gene_variant 0.15
eis 2714309 p.Pro342Thr missense_variant 0.15
folC 2746173 p.Gly476Trp missense_variant 0.29
folC 2746227 p.Gly458Trp missense_variant 0.25
folC 2746272 p.Ala443Ser missense_variant 0.25
pepQ 2859819 c.600G>T synonymous_variant 0.13
ribD 2987154 c.316C>A synonymous_variant 0.25
ribD 2987347 p.Pro170Gln missense_variant 0.18
Rv2752c 3065262 p.Glu310Asp missense_variant 0.12
Rv2752c 3065406 c.786C>A synonymous_variant 0.2
Rv2752c 3065409 p.Phe261Leu missense_variant 0.22
Rv2752c 3065473 p.Ser240Tyr missense_variant 0.17
Rv2752c 3065557 p.Gly212Val missense_variant 0.2
Rv2752c 3065995 p.His66Arg missense_variant 0.12
Rv2752c 3066275 c.-84G>A upstream_gene_variant 0.25
Rv2752c 3066329 c.-138C>A upstream_gene_variant 0.18
thyA 3073832 p.Glu214* stop_gained 0.18
thyA 3073851 p.His207Gln missense_variant 0.25
thyA 3074086 p.Ile129Ser missense_variant 0.12
ald 3086825 c.6C>A synonymous_variant 0.29
ald 3087243 p.Ala142Ser missense_variant 0.23
ald 3087299 p.Met160Ile missense_variant 0.18
fbiD 3339195 c.78G>T synonymous_variant 0.17
fbiD 3339373 p.Glu86* stop_gained 0.14
fbiD 3339472 p.Ala119Pro missense_variant 0.13
Rv3083 3448437 c.-67C>A upstream_gene_variant 0.15
Rv3083 3449034 c.531C>A synonymous_variant 0.18
Rv3083 3449515 p.Glu338Gln missense_variant 0.2
Rv3083 3449825 p.Ser441Tyr missense_variant 0.29
fprA 3473996 c.-11_-10insA upstream_gene_variant 0.26
fprA 3474276 c.270C>A synonymous_variant 0.13
Rv3236c 3612156 p.Arg321Cys missense_variant 0.17
Rv3236c 3612901 c.216C>A synonymous_variant 0.15
Rv3236c 3613204 c.-88G>T upstream_gene_variant 0.17
fbiB 3640839 c.-696C>A upstream_gene_variant 0.15
fbiA 3640876 p.His112Asn missense_variant 0.17
fbiA 3641140 p.Ile200Leu missense_variant 0.29
alr 3840692 c.729C>A synonymous_variant 0.15
alr 3840915 p.Pro169Gln missense_variant 0.2
alr 3841444 c.-24G>T upstream_gene_variant 0.2
rpoA 3877553 p.Glu319* stop_gained 0.17
rpoA 3877692 c.816G>C synonymous_variant 0.14
rpoA 3877888 p.Ala207Glu missense_variant 0.22
rpoA 3877940 p.Asp190Tyr missense_variant 0.15
ddn 3986818 c.-26G>T upstream_gene_variant 0.29
ddn 3987112 p.Leu90Pro missense_variant 0.17
clpC1 4038519 p.Arg729Gln missense_variant 0.17
clpC1 4038530 p.Glu725Asp missense_variant 0.17
clpC1 4038533 p.Arg724Gln missense_variant 0.18
clpC1 4038536 c.2169C>G synonymous_variant 0.17
clpC1 4038551 c.2154C>G synonymous_variant 0.17
clpC1 4038587 c.2118C>T synonymous_variant 0.27
clpC1 4038596 c.2109A>G synonymous_variant 0.23
clpC1 4038605 c.2100G>A synonymous_variant 0.23
clpC1 4038613 p.Asn698His missense_variant 0.23
clpC1 4038614 c.2091C>T synonymous_variant 0.23
clpC1 4038620 p.Gln695Leu missense_variant 0.21
clpC1 4038623 c.2082A>G synonymous_variant 0.21
clpC1 4038640 p.Asp689Asn missense_variant 0.2
clpC1 4038647 c.2058T>C synonymous_variant 0.2
clpC1 4038650 c.2055C>T synonymous_variant 0.2
clpC1 4038749 c.1956C>A synonymous_variant 0.33
clpC1 4038830 c.1875C>T synonymous_variant 0.25
clpC1 4038836 c.1869G>C synonymous_variant 0.22
clpC1 4038845 c.1858_1860delTCGinsAGC synonymous_variant 0.25
clpC1 4038860 c.1845G>C synonymous_variant 0.17
clpC1 4038878 c.1827A>G synonymous_variant 0.17
clpC1 4038881 c.1824C>G synonymous_variant 0.18
clpC1 4038890 c.1815G>A synonymous_variant 0.2
clpC1 4038905 c.1800A>C synonymous_variant 0.22
clpC1 4038908 c.1797C>G synonymous_variant 0.22
clpC1 4038911 c.1794G>T synonymous_variant 0.22
clpC1 4038914 c.1791G>C synonymous_variant 0.22
clpC1 4038917 c.1788C>T synonymous_variant 0.36
clpC1 4038923 c.1782A>G synonymous_variant 0.36
clpC1 4038953 c.1752A>G synonymous_variant 0.23
clpC1 4038956 c.1749T>C synonymous_variant 0.17
clpC1 4039262 c.1443C>T synonymous_variant 0.22
clpC1 4039274 c.1431G>C synonymous_variant 0.22
clpC1 4039277 c.1428C>A synonymous_variant 0.25
clpC1 4039286 c.1419T>C synonymous_variant 0.22
clpC1 4039289 c.1416T>C synonymous_variant 0.2
clpC1 4039292 c.1413C>T synonymous_variant 0.22
clpC1 4039295 c.1410A>C synonymous_variant 0.22
clpC1 4039298 c.1407T>C synonymous_variant 0.22
clpC1 4039310 c.1395A>G synonymous_variant 0.25
clpC1 4039313 c.1392C>G synonymous_variant 0.22
clpC1 4039319 c.1386T>C synonymous_variant 0.25
clpC1 4039454 c.1251A>T synonymous_variant 0.29
clpC1 4039463 c.1242C>G synonymous_variant 0.33
clpC1 4039466 c.1239T>C synonymous_variant 0.33
clpC1 4039469 c.1236T>C synonymous_variant 0.33
clpC1 4039472 c.1233G>C synonymous_variant 0.33
clpC1 4039481 c.1224T>C synonymous_variant 0.33
clpC1 4039484 c.1221T>C synonymous_variant 0.29
clpC1 4039487 c.1218G>C synonymous_variant 0.33
clpC1 4039931 c.774T>C synonymous_variant 0.2
clpC1 4039934 c.771G>C synonymous_variant 0.2
clpC1 4039937 c.768G>C synonymous_variant 0.2
clpC1 4039946 c.759A>C synonymous_variant 0.2
clpC1 4039949 c.756G>C synonymous_variant 0.22
clpC1 4039952 c.753T>C synonymous_variant 0.2
clpC1 4039979 c.726C>G synonymous_variant 0.23
clpC1 4039991 c.714G>C synonymous_variant 0.23
clpC1 4040015 c.690G>C synonymous_variant 0.25
clpC1 4040021 c.684A>C synonymous_variant 0.25
clpC1 4040024 c.681A>G synonymous_variant 0.23
clpC1 4040030 c.675C>G synonymous_variant 0.23
clpC1 4040033 c.672G>C synonymous_variant 0.27
clpC1 4040042 c.663C>T synonymous_variant 0.27
clpC1 4040057 c.648C>T synonymous_variant 0.22
clpC1 4040087 c.618G>C synonymous_variant 0.15
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.15
clpC1 4040093 c.612C>T synonymous_variant 0.15
clpC1 4040144 c.561G>C synonymous_variant 0.2
clpC1 4040147 c.558A>G synonymous_variant 0.2
clpC1 4040153 c.552A>G synonymous_variant 0.2
clpC1 4040159 c.546G>C synonymous_variant 0.2
clpC1 4040162 c.543G>C synonymous_variant 0.2
clpC1 4040165 c.540G>C synonymous_variant 0.18
clpC1 4040168 c.537G>C synonymous_variant 0.15
clpC1 4040219 c.486C>T synonymous_variant 0.25
clpC1 4040453 c.252C>A synonymous_variant 0.15
clpC1 4040830 c.-126G>A upstream_gene_variant 0.15
panD 4043873 p.Gly137Cys missense_variant 0.2
panD 4043898 c.384G>T synonymous_variant 0.15
panD 4044044 p.His80Asn missense_variant 0.17
panD 4044087 c.195C>A synonymous_variant 0.17
panD 4044111 c.171C>A synonymous_variant 0.18
embC 4240228 c.366G>T synonymous_variant 0.13
embC 4240654 c.792C>A synonymous_variant 0.22
embC 4240672 c.810C>A synonymous_variant 0.2
embC 4241143 c.1281C>A synonymous_variant 0.17
embC 4241160 p.Ala433Asp missense_variant 0.17
embC 4241282 p.Ala474Thr missense_variant 0.14
embA 4243260 p.His10Asn missense_variant 0.14
embA 4243328 c.96G>A synonymous_variant 0.17
embA 4243337 c.105G>A synonymous_variant 0.18
embA 4243679 c.447C>A synonymous_variant 0.15
embA 4243826 c.594G>A synonymous_variant 0.2
embA 4243957 p.Pro242Gln missense_variant 0.17
embA 4243970 c.738C>A synonymous_variant 0.18
embA 4245018 p.Gly596Cys missense_variant 0.2
embA 4245053 c.1821G>T synonymous_variant 0.17
embA 4245206 c.1974A>G synonymous_variant 0.18
embA 4245208 p.Leu659Trp missense_variant 0.18
embA 4245778 p.Ala849Asp missense_variant 0.17
embB 4245791 c.-723C>T upstream_gene_variant 0.17
embB 4246448 c.-66C>A upstream_gene_variant 0.14
embB 4246578 p.Ser22Tyr missense_variant 0.4
embB 4247089 c.576G>C synonymous_variant 0.12
embB 4247191 c.678C>A synonymous_variant 0.17
aftB 4266995 c.1842G>C synonymous_variant 0.22
aftB 4267743 p.Arg365Gln missense_variant 0.17
aftB 4267785 p.Gly351Val missense_variant 0.18
aftB 4267961 c.876C>A synonymous_variant 0.2
aftB 4267966 p.Arg291Ser missense_variant 0.2
aftB 4268150 p.Met229Ile missense_variant 0.2
aftB 4269678 c.-842C>A upstream_gene_variant 0.22
ubiA 4269689 p.Val49Ile missense_variant 0.2
ubiA 4269730 p.Ala35Glu missense_variant 0.22
ethA 4326208 c.1266G>T synonymous_variant 0.15
ethA 4326247 p.Met409Ile missense_variant 0.13
ethA 4326376 c.1098G>T synonymous_variant 0.18
ethA 4326448 c.1026G>T synonymous_variant 0.15
ethR 4327102 c.-447G>T upstream_gene_variant 0.17
ethR 4327636 p.Leu30Ile missense_variant 0.25
whiB6 4338538 c.-17T>C upstream_gene_variant 0.33
gid 4407927 p.Glu92Asp missense_variant 0.14