TB-Profiler result

Run: SRR8692907

Summary

Run ID: SRR8692907

Sample name:

Date: 13-08-2023 21:41:23

Number of reads: NA

Percentage reads mapped: NA

Strain: lineage4.9

Drug-resistance: Other


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rplC 801268 p.Cys154Arg missense_variant 0.94 linezolid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
Rv1258c 1406686 p.Val219Ile missense_variant 0.96
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1475759 n.2102C>T non_coding_transcript_exon_variant 0.11
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.12
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.12
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.12
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.12
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 0.14
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.11
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.1
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.13
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.12
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.13
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.12
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.16
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.18
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.18
clpC1 4039694 c.1011G>C synonymous_variant 0.13
clpC1 4039718 c.987C>G synonymous_variant 0.12
clpC1 4039724 c.981A>G synonymous_variant 0.11
clpC1 4039733 c.972G>C synonymous_variant 0.11