TB-Profiler result

Run: SRR8791250
Summary

Run ID: SRR8791250

Sample name:

Date: 18-08-2022 12:25:05

Number of reads: 582589

Percentage reads mapped: 99.8

Strain:

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761128 p.Ser441Leu missense_variant 1.0 rifampicin
pncA 2289057 p.Pro62Leu missense_variant 0.12 pyrazinamide
pncA 2289140 p.Tyr34* stop_gained 1.0 pyrazinamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7585 p.Ser95Thr missense_variant 1.0
fabG1 1673498 p.Val20Gly missense_variant 0.18
katG 2155039 p.Gly358Asp missense_variant 0.13
katG 2155111 p.Glu334Ala missense_variant 0.13