TB-Profiler result

Run: ERR025880
Summary

Run ID: ERR025880

Sample name:

Date: 31-03-2023 08:18:50

Number of reads: 1532231

Percentage reads mapped: 39.15

Strain: lineage2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 1.0
lineage2.1 East-Asian (non-Beijing) None None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 490751 c.-32T>G upstream_gene_variant 0.2
fgd1 491742 c.960T>C synonymous_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 765121 c.1752G>A synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304443 p.Ala505Thr missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474935 n.1278A>C non_coding_transcript_exon_variant 0.29
rrl 1475209 n.1552G>T non_coding_transcript_exon_variant 0.14
inhA 1674952 p.Pro251Ala missense_variant 0.33
rpsA 1834177 c.636A>C synonymous_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102116 c.927G>A synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2155506 c.606C>A synonymous_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2169320 p.Leu431Phe missense_variant 0.4
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2714940 p.Tyr131* stop_gained 0.17
ahpC 2726341 p.Val50Gly missense_variant 0.29
folC 2747263 c.336C>A synonymous_variant 0.19
pepQ 2860118 p.Val101Leu missense_variant 0.18
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339273 c.156T>G synonymous_variant 0.27
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612422 p.Val232Gly missense_variant 0.3
fbiB 3642772 p.Asp413Ala missense_variant 0.38
clpC1 4038857 c.1848C>A synonymous_variant 0.24
clpC1 4040841 c.-138delG upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246088 c.-426A>G upstream_gene_variant 1.0
aftB 4267647 p.Asp397Gly missense_variant 1.0
ubiA 4269520 p.Val105Gly missense_variant 0.22
ubiA 4269529 p.Ala102Gly missense_variant 0.3
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0