TB-Profiler result

Run: ERR038293
Summary

Run ID: ERR038293

Sample name:

Date: 31-03-2023 08:40:33

Number of reads: 10632447

Percentage reads mapped: 99.64

Strain: lineage4.3.3

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.3 Euro-American (LAM) LAM;T RD115 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8040 p.Gly247Ser missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 0.99
rpoB 762249 p.Leu815Val missense_variant 0.2
rpoC 762836 c.-534C>G upstream_gene_variant 0.25
rpoC 764995 c.1626C>G synonymous_variant 0.99
rpoC 767305 p.Tyr1312* stop_gained 0.2
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
atpE 1461019 c.-26C>A upstream_gene_variant 0.23
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1473343 n.1498G>T non_coding_transcript_exon_variant 0.21
rrl 1474380 n.723G>T non_coding_transcript_exon_variant 0.23
rrl 1475363 n.1706C>A non_coding_transcript_exon_variant 0.2
rrl 1476056 n.2399G>A non_coding_transcript_exon_variant 1.0
fabG1 1673449 p.Thr4Pro missense_variant 0.34
inhA 1674892 p.Asn231Asp missense_variant 0.26
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169320 p.Leu431Phe missense_variant 0.16
PPE35 2169866 c.747G>C synonymous_variant 0.36
Rv1979c 2223051 p.Glu38Asp missense_variant 0.99
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518919 p.Gly269Ser missense_variant 1.0
eis 2714366 p.Val323Leu missense_variant 0.23
eis 2715586 c.-254G>C upstream_gene_variant 0.5
pepQ 2859381 c.1038C>G synonymous_variant 0.21
ribD 2986872 p.Thr12Ala missense_variant 1.0
ribD 2987307 p.Ala157Pro missense_variant 0.15
Rv2752c 3064741 p.Gly484Ala missense_variant 0.26
Rv2752c 3065824 p.Pro123Leu missense_variant 1.0
thyA 3073806 c.666C>G synonymous_variant 0.21
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiB 3642734 c.1200G>C synonymous_variant 0.2
fbiB 3642772 p.Asp413Ala missense_variant 0.15
clpC1 4038287 c.2418C>T synonymous_variant 0.99
clpC1 4038857 c.1848C>A synonymous_variant 0.18
clpC1 4039932 p.Gly258Val missense_variant 0.29
embC 4239842 c.-21C>A upstream_gene_variant 0.17
embC 4242425 p.Arg855Gly missense_variant 0.17
embC 4242476 p.Pro872Ala missense_variant 0.26
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242822 p.Val987Gly missense_variant 0.45
embC 4242827 p.Leu989Val missense_variant 0.21
ubiA 4269529 p.Ala102Gly missense_variant 0.24
ethA 4327672 c.-199G>A upstream_gene_variant 0.28
whiB6 4338522 c.-2_-1insGTT upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0