TB-Profiler result

Run: ERR10796548
Summary

Run ID: ERR10796548

Sample name:

Date: 31-03-2023 11:11:08

Number of reads: 794473

Percentage reads mapped: 100.0

Strain: lineage4.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5082 c.-157delC upstream_gene_variant 1.0
gyrB 6507 p.Ala423Val missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7769 c.468C>T synonymous_variant 0.11
gyrA 9165 p.Tyr622His missense_variant 0.2
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9656 c.2355C>G synonymous_variant 1.0
ccsA 619792 c.-99C>T upstream_gene_variant 0.4
rpoB 762958 p.Leu1051Pro missense_variant 0.11
rpoC 765150 p.Gly594Glu missense_variant 1.0
rpoC 765187 c.1818C>T synonymous_variant 1.0
rpoC 766012 c.2643C>G synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781421 c.-139C>A upstream_gene_variant 1.0
rplC 801275 p.Thr156Met missense_variant 0.15
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474198 n.541G>T non_coding_transcript_exon_variant 0.15
rpsA 1833711 c.171delC frameshift_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2156007 c.105C>T synonymous_variant 1.0
Rv1979c 2222451 c.714C>T synonymous_variant 0.11
Rv1979c 2222759 p.Val136Met missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2288993 c.249C>T synonymous_variant 1.0
pepQ 2859857 p.Val188Met missense_variant 0.13
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474235 c.230delG frameshift_variant 0.14
alr 3840605 c.816G>T synonymous_variant 0.13
ddn 3986691 c.-153G>C upstream_gene_variant 0.15
clpC1 4039028 c.1676delA frameshift_variant 0.15
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embA 4243884 p.Met218Leu missense_variant 0.2
embB 4246817 p.Ala102Thr missense_variant 0.13
aftB 4268391 p.Gly149Val missense_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408237 c.-35C>T upstream_gene_variant 0.18