TB-Profiler result

Run: ERR11049021
Summary

Run ID: ERR11049021

Sample name:

Date: 31-03-2023 12:03:52

Number of reads: 3847368

Percentage reads mapped: 99.69

Strain: lineage4.7

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.7 Euro-American (mainly T) T1;T5 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.16
rpoB 760715 c.909C>T synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775878 p.Thr868Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
embR 1416814 c.534G>A synonymous_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474294 n.637C>G non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2167963 p.Gly884Trp missense_variant 1.0
PPE35 2170065 p.Ala183Gly missense_variant 0.25
PPE35 2170675 c.-63G>C upstream_gene_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pepQ 2860159 p.Ala87Gly missense_variant 0.2
fbiD 3339734 p.Ala206Gly missense_variant 0.67
fbiD 3339746 p.Ala210Gly missense_variant 0.36
whiB7 3568428 c.252A>G synonymous_variant 0.29
rpoA 3878613 c.-106A>C upstream_gene_variant 0.22
rpoA 3878618 c.-111A>C upstream_gene_variant 0.3
rpoA 3878641 c.-134C>G upstream_gene_variant 0.47
embC 4240409 p.Pro183Ala missense_variant 0.13
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4249732 c.3219C>G synonymous_variant 1.0
ubiA 4270004 c.-171G>A upstream_gene_variant 0.99
whiB6 4338595 c.-75delG upstream_gene_variant 1.0